反应详情

The product of Example 1B and 2-(4-phenoxyphenyl)acetic acid were treated using a method similar to that described in Example 111 to give the title compound. 1H NMR (500 MHz, DMSO-d6/D2O) δ 8.31 (dd, J=7.9, 0.7, 1H), 8.03 (d, J=7.7, 1H), 8.02-7.96 (m, 1H), 7.95-7.87 (m, 1H), 7.46-7.36 (m, 4H), 7.20-7.12 (m, 1H), 7.05-6.97 (m, 4H), 3.88-3.78 (m, 4H), 3.67 (s, 2H), 3.13-3.05 (m, 4H); MS (ESI−) M/Z 455 (M−H)−.