HRID538784

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID222

Ammonia gas

H3N

HCID76970

5-Chloro-o-anisic acid

C8H7ClO3

结构：CC(C)(C)OC(=O)N1CC(Cn2cc(C(C)(C)C)sc2=N)C1

HCID66660694

未命名化合物

PRODUCTS

生成物

$结构：COc1ccc(Cl)cc1C(=O)/N=c1\sc(C(C)(C)C)cn1CC1CN(C(=O)OC(C)(C)C)C1$

HCID178490662

未命名化合物

PROCEDURE

实验过程

The title compound was prepared according to the procedure described in Example 54A by substituting 5-chloro-2-methoxybenzoic acid for Example 26B and the product of Example 63A for Example 16A. 1H NMR (300 MHz, CHLOROFORM-D) δ ppm 1.34 (s, 9H) 1.44 (s, 9H) 3.10-3.30 (m, 1H) 3.77 (dd, J=9.12, 5.16 Hz, 2H) 3.90 (s, 3H) 4.05 (t, J=8.53 Hz, 2H) 4.37 (s, 2H) 6.63 (s, 1H) 6.91 (d, J=8.73 Hz, 1H) 7.33 (dd, J=8.72, 2.78 Hz, 1H) 7.89 (d, J=2.78 Hz, 1H). MS (DCI/NH3) m/z 494.2 (M+H)+.