反应详情

Following general procedure B2 and D1, 3-(2,4-Dimethoxy-benzyloxy)-1H-benzo[4,5]furo[3,2-d]pyrimidine-2,4-dione was alkylated with allyl bromide and subsequently deprotected to provide the title compound as a white solid. 1H NMR (d6-DMSO, 300 MHz) δ 4.92-4.94 (m, 2H); 5.09-5.18 (m, 2H); 6.03-6.16 (m, 1H); 7.45 (dd, J=8 Hz, 1H); 7.65 (dd, J=8 Hz, 1H); 7.81 (d, J=8 Hz, 1H); 7.98 (d, J=8 Hz, 1H); Ret. time=1.94 min., m/z=259.0.