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HRID552235

反应详情

EQUATION

反应方程式

HRID 552235 的结构方程式

REACTANTS

反应物

2
结构：CC(C)C(C=O)NC(=O)OC(C)(C)C
HCID545985

tert-butyl 3-methyl-1-oxobutan-2-ylcarbamate

C10H19NO3

结构：CC(C)(C)OC(=O)N1CC(C)(C)OCC1C(=O)Nc1cc(Cl)cc2c1[nH]c1cnccc12
HCID67164497

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)C(N)CN1CC(C)(C)OCC1C(=O)Nc1cc(Cl)cc2c1[nH]c1cnccc12
HCID67165123

未命名化合物

PROCEDURE

实验过程

Method C was followed, using 5-(6-chloro-9H-β-carbolin-8-ylcarbamoyl)-2,2-dimethyl-morpholine-4-carboxylic acid tert-butyl ester and the appropriate aldehyde, (1-formyl-2-methyl-propyl)-carbamic acid tert-butyl ester. 1H-NMR (DMSO-d6, 300 MHz) δ 9.05 (s, 1); 8.37 (d, 1); 8.21 (d, 1); 8.16 (dd, 1); 7.90 (d, 1); 6.71 (br s, 2); 3.93-3.86 (m, 2); 3.18-3.14 (m, 1); 2.91 (d, 1); 2.70-2.65 (m, 2); 2.21 (dd, 1); 2.15 (d, 1); 1.74-1.66 (m, 1); 1.31 (s, 3); 1.19 (s, 3); 0.85 (d, 3); 0.80 (d, 3). NH4OAc standard conditions. DAD Rf=1.27 min. M+H=444.