反应详情

A procedure similar to step 2 of Example 1 was used, the 3-(4-nitro-phenyl)-propionyl chloride prepared in the step 2 and methylphenyl ether were used as starting materials, and anhydrous AlCl3 was used as catalyst, the obtained product was white solid in a yield of 81.3%, mp: 123-125 └. 1H-NMR (CDCl3, 400 MHz) δ: 3.18 (2H, t, J=7.00 Hz), 3.30 (2H, t, J=7.00 Hz), 3.87 (3H, s, OCH3), 6.93 (2H, d, J=8.96 Hz, ArH), 7.42 (2H, d, J=8.60 Hz, ArH), 7.93 (2H, d, J=8.96 Hz, ArH), 8.15 (2H, d, J=8.60 Hz, ArH); EI-MS m/e (%): 285.0 (M+, 62), 134 (100).