反应详情

lnto a flask equipped with a stirrer and a thermometer, dl-2-allyl-3-hydroxy-3-methyl-4-cyclopentenone (152 g), p-toluenesulfonic acid (1 g) and acetic anhydride (320 g) were charged, and the resultant mixture was stirred at 100° C. for 2 hours. After completion of the reaction, acetic anhydride was removed under reduced pressure, and the residue was extracted with toluene. The toluene layer was washed with 1% sodium bicarbonate solution and water in order. Toluene was removed from the toluene layer to give dl-3-acetoxy-2-allyl-3-methyl-4-cyclopentenone (186 g). Yield, 96%. B.P., 72°-75° C./0.2-0.3 mmHg.

1. customlnto a flask equipped with a stirrer
2. customwas removed under reduced pressure
3. extractionthe residue was extracted with toluene
4. washThe toluene layer was washed with 1% sodium bicarbonate solution and water in order
5. customToluene was removed from the toluene layer