反应详情

4-benzyloxy-3-formylamino-α-[N-benzyl-N-(1-methyl-2-p-methoxyphenylethyl)aminomethyl]benzyl alcohol (120 gms, 0.23 M), 10% Pd/C (12 gms) and denatured spirit (0.6 lit) were introduced in an autoclave. The reaction mass was hydrogenated by applying 4 kg hydrogen pressure at 25-30° C. for 3 hrs. The catalyst was removed by filtration and the clear filtrate concentrated under reduced pressure below 40° C. to yield the title compound. (63 gms, 80%).

1. additionwere introduced in an autoclave
2. customat 25-30° C.
3. customfor 3 hrs
4. customThe catalyst was removed by filtration
5. concentrationthe clear filtrate concentrated under reduced pressure below 40° C.