反应详情

The title compound was prepared according to the procedure described for Example 13 using benzyl isocyanate (0.4 g, 3.2 mmol) and 5-methyl-4-amino-thiophene-2-carboxylic acid methyl ester from Step 1 to afford 0.77 g of 5-methyl-4-(3-benzyl-ureido)-thiophene-2-carboxylic acid methyl ester. Recrystallization of a sample from acetonitrile gave product with a mp 185-187° C.

1. customThe title compound was prepared