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HRID601176

反应详情

EQUATION

反应方程式

HRID 601176 的结构方程式

REACTANTS

反应物

4
结构：Nc1ccccc1S(N)(=O)=O
HCID72894

2-Aminobenzenesulfonamide

C6H8N2O2S

结构：Nc1ccc(Br)cc1S(N)(=O)=O
HCID820700

2-amino-5-bromobenzenesulfonamide

C6H7BrN2O2S

结构：CCOC(=O)c1c(O)c2cc(Cl)cnc2n(Cc2ccccc2)c1=O
HCID54692180

Ethyl 1-benzyl-6-chloro-4-hydroxy-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxylate

C18H15ClN2O4

结构：CCOC(=O)c1c(O)c2cccnc2n(Cc2ccccc2)c1=O
HCID54729304

Ethyl 1-benzyl-4-hydroxy-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxylate

C18H16N2O4

PRODUCTS

生成物

1
结构：NS(=O)(=O)c1ccccc1NC(=O)c1c(O)c2cc(Cl)cnc2n(Cc2ccccc2)c1=O
HCID67064084

未命名化合物

PROCEDURE

实验过程

The title compound was prepared according to the procedure of Example 84C substituting ethyl 1-benzyl-6-chloro-4-hydroxy-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxylate for the product of Example 84B and substituting 2-amino-benzenesulfonamide for the product of Example 84A. 1H NMR (300 MHz, DMSO-d6) δ ppm 5.64 (s, 2 H) 7.25 (m, 5 H) 7.44 (t, J=7.72 Hz, 1 H) 7.52 (s, 2 H) 7.67 (m, 1 H) 7.93 (m, 2 H) 8.56 (d, J=2.57 Hz, 1 H) 8.87 (d, J=2.57 Hz, 1 H) 12.34 (s, 1 H) 16.76 (s, 1 H).