HRID605016
反应详情
EQUATION
反应方程式
REACTANTS
反应物
PRODUCTS
生成物
AUXILIARIES
试剂、催化剂与溶剂
PROCEDURE
实验过程
2-[4-({4-[5-(6-methoxypyridin-3-yl)-4H-1,2,4-triazol-3-yl]piperidin-1-yl}methyl)phenyl]-3-phenyl-1,6-naphthyridin-5(6H)-one (300 mg, 0.53 mmol) was dissolved in MeOH and TFA (40 μL, 0.53 mmol) was added. The solvent was evaporated under reduced pressure and the yellow residue was dried under high vacuum for 16 h to give 2-[4-({4-[5-(6-methoxypyridin-3-yl)-4H-1,2,4-triazol-3-yl]piperidin-1-yl}methyl)phenyl]-3-phenyl-1,6-naphthyridin-5(6H)-one trifluoroacetate.
WORKUP
后处理
- customThe solvent was evaporated under reduced pressure
- customthe yellow residue was dried under high vacuum for 16 h