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HRID61249

反应详情

EQUATION

反应方程式

HRID 61249 的结构方程式

REACTANTS

反应物

3
结构：O=C(O)c1ccccc1I
HCID6941

Benzoic acid, 2-iodo-

C7H5IO2

结构：Fc1ccc(C(F)(F)F)cn1
HCID5463754

2-Fluoro-5-(trifluoromethyl)pyridine

C6H3F4N

结构：C[C@@H]1CCCN(C(=O)c2ccccc2-c2ncccn2)[C@@H]1CN
HCID117727638

未命名化合物

PRODUCTS

生成物

1
结构：C[C@@H]1CCCN(C(=O)c2ccccc2-c2ncccn2)[C@@H]1CNc1ccc(C(F)(F)F)cn1
HCID117728095

未命名化合物

PROCEDURE

实验过程

The title compound was prepared following the same general protocol as described for Example A230 using 2-iodobenzoic acid to make ((2S,3R)-2-(aminomethyl)-3-methylpiperidin-1-yl)(2-(pyrimidin-2-yl)phenyl)methanone and 2-fluoro-5-(trifluoromethyl)pyridine. ESI-MS (m/z): 456 [M+1]+. 1H NMR (500 MHz, DMSO-d6) δ 8.90-6.60 (m, 11H), 4.85-2.85 (m, 5H), 2.00-0.65 (m, 8H).