反应详情

The title compound was prepared using 6-bromo-4-chloro-3-phenylquinoline (Intermediate 3, step c) and (3-methoxyphenyl)(pyridin-3-yl)methanone in place of 6-bromo-2,4-dichloro-3-phenylquinoline and (3-chlorophenyl)(pyridin-3-yl)methanone, respectively, according to the procedure described in Example 25. 1H NMR (400 MHz, CDCl3) δ 8.83 (s, 1H), 8.61-8.65 (m, 1H), 8.53-8.57 (m, 1H), 8.37 (d, J=1.96 Hz, 1H), 8.09 (d, J=9.05 Hz, 1H), 7.68-7.75 (m, 2H), 7.50-7.55 (m, 5H), 7.26-7.30 (m, 2H), 6.83-6.91 (m, 3H), 3.75 (s, 3H); MS m/e 452.9 [M+H]+.