HRID638816
反应详情
EQUATION
反应方程式
REACTANTS
反应物
PRODUCTS
生成物
PROCEDURE
实验过程
(11β,16α,17β)-11-(4-Bromophenyl)-17-cyclopropylcarbonyl-16-methylestra-4,9-dien-3-one and 5-methoxy-3-pyridinylboronic acid were used as described in example 1 step h. Purification by LCMS followed by lyophilisation gave the product (41% yield). 1H NMR (400 MHz, CDCl3): δ 0.35 (s, 3H), 0.80-2.86 (m, 24H), 3.92 (s, 3H), 4.46 (d, J=7 Hz, 1H), 5.80 (s, 1H), 7.24-7.29 (m, 2H), 7.35 (dd, J=3 and 1 Hz, 1H), 7.48-7.53 (m, 2H), 8.28 (d, J=3 Hz, 1H), 8.45 (d, J=1 Hz, 1H).
WORKUP
后处理
- customPurification by LCMS