HRID639262
反应详情
EQUATION
反应方程式
REACTANTS
反应物
PRODUCTS
生成物
PROCEDURE
实验过程
The title compound was prepared in the manner of Example 36 from 2,2,2-trichloro-1-{10-[(2-methoxy-2′-methyl-1,1′-biphenyl-4-yl)carbonyl]-10,11-dihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-3-yl}ethanone of Example 35 and C-(2,3-dihydrobenzo[1,4]dioxin-6-yl)-methylamine. Purification was performed using HPLC with a normal phase column and eluting with a two phase solvent system (A=hexane, B=dichloromethane/methanol, 4:1), m.p. 153-155° C. MS [(+)ESI, m/z]: 600 [M+H]+
WORKUP
后处理
- customPurification
- washeluting with a two phase solvent system (A=hexane, B=dichloromethane/methanol, 4:1), m.p. 153-155° C