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HRID651652

反应详情

EQUATION

反应方程式

HRID 651652 的结构方程式

REACTANTS

反应物

2
结构：CC(C)(C)OC(=O)N[C@H]1CCNC1=O
HCID10750535

tert-Butyl [(3S)-2-oxopyrrolidin-3-yl]carbamate

C9H16N2O3

结构：O=S(=O)(c1ccccc1)n1c(CBr)cc2nc(Cl)ccc21
HCID18176356

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)N[C@H]1CCN(Cc2cc3nc(Cl)ccc3n2S(=O)(=O)c2ccccc2)C1=O
HCID53857962

未命名化合物

PROCEDURE

实验过程

The title compound is prepared from (2-oxopyrrolidin-3-(S)-yl)-carbamic acid tert-butyl ester as described in EXAMPLE 1, Part H using 1-benzenesulfonyl-2-bromomethyl-5-chloro-1H-pyrrolo[3,2-b]pyridine in place of 7-bromomethyl-1-chloro-isoquinoline. The crude product is purified by column chromatography eluting with a gradient of 15% EtOAc/hexanes to 50% EtOAc/hexanes to give the title compound as a beige solid.

WORKUP

后处理

  1. customThe crude product is purified by column chromatography
  2. washeluting with a gradient of 15% EtOAc/hexanes to 50% EtOAc/hexanes