反应详情

When the product of Step D was substituted for tert-butyl 2,2-dimethyl-5-((4-octylphenylamino)methyl)-1,3-dioxan-5-ylcarbamate in Example 1, Step B, the identical process afforded the title compound in 68% yield, as a creamy solid. 1H-NMR (CDCl3) 1.77 (broad s, 4H+H2O); 2.79 (s, 4H); 2.96 (tr, 2H, J=8.3 Hz); 3.07 (s, 2H); 3.44 (tr, 2H, J=8.3 Hz); 3.57-3.61 (m, 4H); 3.82 (m, 9H); 6.38 (s, 2H); 6.55 (d, 1H, J=7.95 Hz); 6.9 (d, 1H, J=7.95 Hz); 7.03 (s, 1H).