HRID710339

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COc1ccc2c(C(=O)c3cc(OC)c(OC)c(OC)c3)cn(S(=O)(=O)c3ccc(CCC4(NC(=O)OC(C)(C)C)COC(C)(C)OC4)cc3)c2c1

HCID131733939

未命名化合物

结构：COc1cccc(N(C)S(=O)(=O)c2ccc(CCC3(NC(=O)OC(C)(C)C)COC(C)(C)OC3)cc2)c1

HCID131733943

未命名化合物

PRODUCTS

生成物

结构：COc1cccc(N(C)S(=O)(=O)c2ccc(CCC(N)(CO)CO)cc2)c1

HCID58078807

未命名化合物

收率 80%

PROCEDURE

实验过程

When the product of Step D was substituted for tert-butyl-5-(4-(6-methoxy-3-(3,4,5-trimethoxybenzoyl)-1H-indol-1-ylsulfonyl)phenethyl)-2,2-dimethyl-1,3-dioxan-5-ylcarbamate in Example 13, Step F, the similar process afforded the title compound in 80% yield, as colourless solid. 1H-NMR (CDCl3) 1.87-1.93 (m, 2H); 2.65-2.71 (m, 2H); 3.05 (s, 3H); 3.62 (s, 3H); 3.70 (5, 4H); 6.55 (tr, 1H, J=2.20 Hz); 6.62 (d, 1H, J=7.62 Hz); 6.85 (dd, 1H, J=2.41, 8.34 Hz); 7.19 (tr, 1H, J=8.22 Hz); 7.34 (d, 2H, J=8.36 Hz); 7.43 (d, 2H, J=8.31 Hz).