反应详情

When the product of Step A was substituted for tert-butyl-5-(4-(6-methoxy-3-(3,4,5-trimethoxybenzoyl)-1H-indol-1-ylsulfonyl)-phenethyl)-2,2-di methyl-1,3-dioxan-5-ylcarbamate in Example 13, Step F, the similar process afforded the title compound in 67% yield, as colourless solid. 1H-NMR (CDCl3) 3.17-3.23 (m, 2H); 3.63 (s, 3H); 3.94-3.88 (m, 2H); 4.91 (d, 2H, J=12.36 Hz); 4.97 (d, 2H, J=11.94 Hz); 8.12 (tr, 4H, J=10.92 Hz); 8.66-8.88 (m, 4H).