反应详情

When the product of Step C was substituted for tert-butyl-5-(4-(6-methoxy-3-(3,4,5-trimethoxybenzoyl)-1H-indol-1-ylsulfonyl)-phenethyl)-2,2-dimethyl-1,3-dioxan-5-ylcarbamate in Example 13, Step F, the similar process afforded the title compound in 80% yield, as colourless solid. 1H-NMR (D2O) 0.67 (s, 3H); 0.94 (s, 3H); 1.14-1.17 (m, 2H); 1.71 (m, 6H); 1.88-2.01 (b, 4H); 2.17 (m, 1H); 2.67-2.78 (m, 4H); 3.68 (s, 4H); 7.42 (d, 2H, J=8.17 Hz); 7.70 (d, 2H, J=8.18 Hz).