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HRID710414

反应详情

EQUATION

反应方程式

HRID 710414 的结构方程式

REACTANTS

反应物

2
结构：CCOc1ccc(-c2nc(-c3cccc4c3CCN4CC3(NC(=O)OC(C)(C)C)COC(C)(C)OC3)no2)cc1OCC
HCID66726782

未命名化合物

结构：CCOc1ccc(-c2nc(-c3cccc4c3ccn4CC3(NC(=O)OC(C)(C)C)COC(C)(C)OC3)no2)cc1Cl
HCID131733958

未命名化合物

PRODUCTS

生成物

1
结构：CCOc1ccc(-c2nc(-c3cccc4c3ccn4CC(N)(CO)CO)no2)cc1Cl
HCID46195317

未命名化合物

收率 83.3%

PROCEDURE

实验过程

When the product of Step D was substituted for tert-butyl 5-((4-(5-(3,4-diethoxyphenyl)-1,2,4-oxadiazol-3-yl)indolin-1-yl)methyl)-2,2-dimethyl-1,3-dioxan-5-ylcarbamate in Example 34, Step E, the identical process afforded the title compound in 83.3% yield, as off white solid. 1H-NMR (DMSO-d6) 1.46 (tr, 3H, J=6.85 Hz); 2.99-3.44 (m, 4H); 3.52 (tr, 2H, J=8.96 Hz); 3.71 (tr, 4H, J=10.46 Hz); 4.15 (q, 2H, J=6.97, 13.97 Hz); 6.77 (d, 1H, J=8.12 Hz); 6.99 (d, 1H, J=8.65 Hz); 7.17 (tr, 2H, J=7.74 Hz); 7.45 (d, 1H, J=8.68 Hz); 7.98 (d, 1H, J=8.75 Hz); 8.14, (broad s, 1H).