反应详情

The synthetic procedure was identical to that described for the preparation of 1a, where 1-bromohexane is used in place of 1-bromobutane. Yield: 63%; IR (NaCl, v: cm−1): 1698 (—NHC(═O)H); 1630 (C═C); 1H-NMR (CDCl3, δ: ppm): 8.31, 8.14 (2s, 1H, —C(═O)H); 7.25–7.16, 6.61–6.52 (m, 1H, H2C═CH—); 4.65–4.54 (m, 1H, HaHbC═CH—); 4.45–4.42 (s, 1H, HaHbC═CH—); 3.60–3.44 (t, 2H, —NCH2CH2—); 1.65–1.56 (m, 2H, —CH2CH2CH2—); 1.31 (m, 6H, —CH2(CH2)3CH3); 0.90–0.88 (t, 3H, —NCH2CH2(CH2)3CH3).