HRID733560
反应详情
EQUATION
反应方程式
REACTANTS
反应物
PRODUCTS
产物
AUXILIARIES
试剂、催化剂与溶剂
PROCEDURE
实验过程
The titled compound was prepared following the procedure C using N-{4-[(4-butylphenyl)ethynyl]benzyl}-N-(2,2-dimethyl-4-oxo-4H-1,3-benzodioxin-6-yl)-4-hexylbenzamide and NaOH 5M aq. in the presence of EtOH as a grey powder (43%). 1H NMR (CDCl3, 300 MHz) δ 10.46 (s, 1H), 7.46 (m, 5H), 7.27 (m, 4H), 7.16 (d, J=7.9 Hz, 2H), 7.00 (m, 3H), 6.76 (d, J=9.0 Hz, 1H), 5.10 (s, 2H), 2.62 (t, J=7.6 Hz, 2H), 2.52 (t, J=7.7 Hz, 2), 1.58 (m, 4H), 1.36 (m, 2H), 1.24 (brs, 6H), 0.93 (t, J=7.2 Hz, 3H), 0.85 (t, J=6.8 Hz, 3H). M− (ESI): 586.3; M1(ESI): 588.2. HPLC, Rt: 6.04 min (Purity: 98.3%).