反应详情

The titled compound was prepared following the procedure B using 6-({4-[(4-chlorophenyl)ethynyl]benzyl}amino)-2,2-dimethyl-4H-1,3-benzodioxin-4-one and 3-cyclopentylpropanoyl chloride as a white foam (80%). 1H NMR (CDCl3, 300 MHz) δ 7.67 (m, 1H), 7.42 (m, 4H), 7.31 (m, 2H), 7.17 (d, J=7.9 Hz, 2H), 7.06 (m, 1H), 6.89 (d, J=8.7 Hz, 1H), 4.86 (s, 2H), 2.06 (m, 2H), 1.73 (s, 6H), 1.66-1.39 (m, 9H), 0.95 (m, 2H). M+ (ESI): 542.1. HPLC, Rt: 5.83 min (Purity: 97.3%).