反应详情

Following a procedure similar to that described in Example 1(b), 860 mg of 2-{2-[4-(2-chlorophenyl)butyl]phenoxymethyl}oxirane [prepared as described in step (a) above] dissolved in 20 ml of tetrahydrofuran were treated with 4 ml of 50% by volume aqueous dimethylamine. The crude product thus obtained was purified as described in Example 1(b), to give 790 mg (yield 80%) of the title compound as a colorless oil.

1. customThe crude product thus obtained
2. customwas purified