反应详情

Following a procedure similar to that described in the latter part of Preparation 3, 4.53 g of this 1-(2-benzyloxyphenyl)-4-(2-chlorophenyl)butadiene were dissolved in a 4:1 by volume mixture of tetrahydrofuran and ethanol and were hydrogenated, whilst ice-cooling. The reaction mixture was then worked up as described in the latter part of Preparation 3, to give 2.86 g (yield 62%) of 1-(2-benzyloxyphenyl)-4-(2-chlorophenyl)butane.

1. temperaturewhilst ice-cooling
2. customas described in the latter part of Preparation 3