HRID749427

反应详情

EQUATION

反应方程式

HRID 749427 的结构方程式

PROCEDURE

实验过程

The compound was synthesized in an analogous way to that of Method 3e but using tert-butyl {(2S)-2-(3,4-dichlorophenyl)-4-[3-(4-fluoropiperidin-1-yl)azetidin-1-yl]butyl}methylcarbamate rather than tert-butyl [2-(4-fluorophenyl)-4-(3-thiomorpholin-4-ylazetidin-1-yl)butyl]methylcarbamate (yield, 100%). 1H NMR (500 MHz, CD3OD): 1.9-2s 2.4 (m, 6H), 2.7 (s, 3H), 3.1-5.1 (cm, 15H), 7.4 (d, 1H), 7.7 (m, 2H), LCMS: m/z 389 (M+1)+.

WORKUP

后处理

  1. customThe compound was synthesized in an analogous way to that of Method 3e