HRID749460

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：C=CC[C@H](CN(C)C(=O)c1cc(Cl)cc(Cl)c1)c1ccc(F)cc1

HCID68978638

未命名化合物

结构：C=CC[C@H](CN(CC)C(=O)c1cc(C#N)cc2c1CCCC2)c1ccc(F)cc1

HCID68978700

未命名化合物

PRODUCTS

生成物

结构：CCN(C[C@@H](CC=O)c1ccc(F)cc1)C(=O)c1cc(C#N)cc2c1CCCC2

HCID58683529

未命名化合物

PROCEDURE

实验过程

The compound was synthesized in an analogous way to that of Method 21b but using 3-cyano-N-ethyl-N-[(2S)-2-(4-fluorophenyl)pent-4-en-1-yl]-5,6,7,8-tetrahydronaphthalene-1-carboxamide rather than 3,5-dichloro-N-[(2S)-2-(4-fluorophenyl)pent-4-en-1-yl]-N-methylbenzamide (yield, 70%). 1H NMR (500 MHz, CDCl3): 0.9-4.2 (cm, 18H), 5.9 (s, <1H), 6.9-7.5 (cm, 6H), 8.0 (s, <1H), 9.7 (m, 1H). LCMS: m/z 393 (M+1)+.

WORKUP

后处理

customThe compound was synthesized in an analogous way to that of Method 21b