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HRID79634

反应详情

EQUATION

反应方程式

HRID 79634 的结构方程式

REACTANTS

反应物

2
结构：CC(C)(C)OC(=O)N1CCCC1c1ncc(-c2ccc(Oc3cccc(-c4cnc(C5CCCN5C(=O)OC(C)(C)C)[nH]4)c3)cc2)[nH]1
HCID66620215

未命名化合物

结构：COC(=O)NC(C(=O)N1CCC(c2ncc(-c3ccc(-c4ccc(-c5cnc(C6CCCN6C(=O)C(NC(=O)OC)C(C)C)[nH]5)cc4)cc3)[nH]2)C1)C(C)C
HCID66620702

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)NC(C(=O)N1CCCC1c1ncc(-c2ccc(Oc3cccc(-c4cnc(C5CCCN5C(=O)C(NC(=O)OC)C(C)C)[nH]4)c3)cc2)[nH]1)C(C)C
HCID66621096

未命名化合物

PROCEDURE

实验过程

Following the procedure used to prepare compound (1-{3-[5-(4′-{2-[1-(2-methoxycarbonylamino-3-methyl-butyryl)-pyrrolidin-2-yl]-3H-imidazol-4-yl}-biphenyl-4-yl)-1H-imidazol-2-yl]-pyrrolidine-1-carbonyl}-2-methyl-propyl)-carbamic acid methyl ester, except that 2-[5-(4-{3-[2-(1-Boc-pyrrolidin-2-yl)-3H-imidazol-4-yl]-phenoxy}-phenyl)-1H-imidazol-2-yl]-pyrrolidine-1-carboxylic acid tert-butyl ester was used instead of 2-(5-{4′-[2-(1-Boc-pyrrolidin-3-yl)-3H-imidazol-4-yl]-biphenyl-4-yl}-1H-imidazol-2-yl)-pyrrolidine-1-carboxylic acid tert-butyl ester. 1H-NMR (300 MHz, CD3OD) δ 7.80-7.10 (m, 10H), 5.30-5.15 (m, 2H), 4.30-4.20 (m, 2H), 4.18-4.05 (m, 2H), 3.95-3.80 (m, 2H), 3.70-3.60 (m, 6H), 2.65-2.45 (m, 2H), 2.40-2.00 (m, 8H), 1.05-0.85 (m, 12H); m/z 755.3 (M+H)+.