反应详情

3.0 g (0.011 mol) of 2-propionyl-5-(3-tetrahydrothiopyranyl)-cyclohexane-1,3-dione and 3.0 g (0.013 mol) of 3-(4-bromophenyl)-prop-2-enyloxyamine in 100 ml of methanol were stirred for 16 hours at 20° C. The precipitated reaction product was filtered off under suction at 0° C. and washed with ice cold methanol and petroleum ether. Drying gave 3.7 g (68.4% of theory) of 2-[1-(3-(4-bromophenyl)-prop-2-enyloximino)-propyl]-3-hydroxy-5-(3-tetrahydrothiopyranyl)-cyclohex-2-en-1-one of melting point 97°-99° C.

1. customThe precipitated reaction product
2. filtrationwas filtered off under suction at 0° C.
3. washwashed with ice cold methanol and petroleum ether
4. customDrying