反应详情

4-(4-(2-Methoxyphenyl)piperazin-1-yl)butan-1-ol (21c) (Scheme 4) was synthesized from 17c according to the protocol described for 21a (Example 31). Colorless oil, 0.8 g (93%). 1H NMR (400 MHz, CDCl3): δ 1.59-1.66 (m, 4H); 2.41-2.43 (m, 2H); 2.68 (broad s, 4H); 3.08 (broad s, 4H); 3.54-3.55 (m, 2H); 3.81 (s, 3H); 5.76 (broad s, 1H); 6.79-6.97 (m, 4H). MS (ESI): m/z=265.40 (M+H+).