HRID889360

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CS(=O)(=O)Nc1cccc(CNC(=O)c2ccc(Cl)nc2)c1

HCID21914545

未命名化合物

2 次

结构：Cc1ccc(NC(=O)c2ccoc2)cc1B1OC(C)(C)C(C)(C)O1

HCID21914573

未命名化合物

2 次

PRODUCTS

生成物

结构：Cc1ccc(NC(=O)c2ccoc2)cc1-c1ccc(C(=O)NCc2cccc(NS(C)(=O)=O)c2)cn1

HCID21914567

未命名化合物

PROCEDURE

实验过程

6-[5-(Fur-3-ylcarbonylamino)-2-methyl-phenyl]-N-(3-methylsulphonylaminobenzyl)-nicotinamide was prepared from 6-chloro-N-(3-methylsulphonylaminobenzyl)nicotinamide (Intermediate 4) and N-[4-methyl-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-3-furamide (Intermediate 13) using General Method B. LCMS: retention time 2.93 min, MH+ 505. NMR: δH [2H6]-DMSO 9.99,(1H, s), 9.32,(1H, t), 9.15,(1H, d), 8.95,(1H, b), 8.38,(1H, s), 8.33,(1H, dd), 7.81,(2H, d), 7.75,(1H, d), 7.68,(1H, d), 7.33-7.30,(2H, m), 7.21,(1H, s), 7.11,(2H, m), 7.01,(1H, s), 4.51,(2H, d), 2.99,(3H, s), 2.32,(3H, s).