HRID891094

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID2777211

4-(Trifluoromethoxy)benzenesulfonamide

C7H6F3NO3S

结构：Cc1nn(-c2ccc(CCNC(=O)Oc3ccccc3)cc2)c(C)c1-c1ccccc1

HCID22244550

未命名化合物

PRODUCTS

生成物

结构：Cc1nn(-c2ccc(CCNC(=O)NS(=O)(=O)c3ccc(OC(F)(F)F)cc3)cc2)c(C)c1-c1ccccc1

HCID10289728

未命名化合物

PROCEDURE

实验过程

The title compound was prepared according to the procedure described in step 2 of Example 22 from phenyl 2-[4-(3,5-dimethyl-4-phenyl-1H-pyrazol-1-yl)phenyl]ethylcarbamate (step 1 of Example 22) and 4-[(trifluoromethyl)oxy]benzenesulfonamide: 1H-NMR (CDCl3) δ 7.98 (2H, d, J=9.1 Hz), 7.47-7.21 (11H, m), δ 12 (1H, br.s), 3.50-3.43 (2H, m), 2.85 (2H, t, J=6:5 Hz). 2.32 (3H, s), 2.23 (3H, s).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-01f22edab81141a88b0fd128b2f72ae4
来源数据集: uspto-grants-2006_02
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07001917B2
来源说明: uspto-grants-2006_02

反应 SMILES

[CH3:1][C:2]1[C:6]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)=[C:5]([CH3:13])[N:4]([C:14]2[CH:19]=[CH:18][C:17]([CH2:20][CH2:21][NH:22][C:23](=O)[O:24]C3C=CC=CC=3)=[CH:16][CH:15]=2)[N:3]=1.[F:32][C:33]([F:46])([F:45])[O:34][C:35]1[CH:40]=[CH:39][C:38]([S:41]([NH2:44])(=[O:43])=[O:42])=[CH:37][CH:36]=1>>[CH3:1][C:2]1[C:6]([C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=2)=[C:5]([CH3:13])[N:4]([C:14]2[CH:15]=[CH:16][C:17]([CH2:20][CH2:21][NH:22][C:23]([NH:44][S:41]([C:38]3[CH:39]=[CH:40][C:35]([O:34][C:33]([F:32])([F:45])[F:46])=[CH:36][CH:37]=3)(=[O:42])=[O:43])=[O:24])=[CH:18][CH:19]=2)[N:3]=1