HRID891142

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID120313

4-(Methanesulfonyl)benzene-1-sulfonamide

C7H9NO4S2

结构：Cc1nn(-c2ccc(CCNC(=O)Oc3ccccc3)cc2)c(C)c1-c1ccccc1

HCID22244550

未命名化合物

PRODUCTS

生成物

结构：Cc1nn(-c2ccc(CCNC(=O)NS(=O)(=O)c3ccc(S(C)(=O)=O)cc3)cc2)c(C)c1-c1ccccc1

HCID22244530

未命名化合物

PROCEDURE

实验过程

The title compound was prepared according to the procedure described in step 2 of Example 22 from phenyl 2-[4-(3,5-dimethyl-4-phenyl-1H-pyrazol-1-yl)phenyl]ethylcarbamate (step 1 of Example 22) and 4-(methylsulfonyl)benzenesulfonamide: 1H-NMR (CDCl3) δ 8.16-8.08 (4H, m), 7.47-7.20 (9H, m), 6.04 (1H, br.s), 3.46-3.41 (2H, m), 3.10 (3H, s), 2.87-2.82 (2H, m), 2.33 (3H, s), 2.22 (3H, s).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-0f948a38073e4e1ca1352b2b8ebf8591
来源数据集: uspto-grants-2006_02
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07001917B2
来源说明: uspto-grants-2006_02

反应 SMILES

[CH3:1][C:2]1[C:6]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)=[C:5]([CH3:13])[N:4]([C:14]2[CH:19]=[CH:18][C:17]([CH2:20][CH2:21][NH:22][C:23](=[O:31])OC3C=CC=CC=3)=[CH:16][CH:15]=2)[N:3]=1.[CH3:32][S:33]([C:36]1[CH:41]=[CH:40][C:39]([S:42]([NH2:45])(=[O:44])=[O:43])=[CH:38][CH:37]=1)(=[O:35])=[O:34]>>[CH3:1][C:2]1[C:6]([C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=2)=[C:5]([CH3:13])[N:4]([C:14]2[CH:19]=[CH:18][C:17]([CH2:20][CH2:21][NH:22][C:23]([NH:45][S:42]([C:39]3[CH:38]=[CH:37][C:36]([S:33]([CH3:32])(=[O:35])=[O:34])=[CH:41][CH:40]=3)(=[O:44])=[O:43])=[O:31])=[CH:16][CH:15]=2)[N:3]=1