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HRID927791

反应详情

EQUATION

反应方程式

HRID 927791 的结构方程式

REACTANTS

反应物

2
结构：CC(C)(C)[Si](C)(C)O[C@H]1CCNC1
HCID15385422

(3S)-3-{[tert-Butyl(dimethyl)silyl]oxy}pyrrolidine

C10H23NOSi

结构：Cc1nc(C(C)(C)NC(=O)c2ccc(Br)c(OCC3CC3)n2)no1
HCID71093545

未命名化合物

PRODUCTS

生成物

1
结构：Cc1nc(C(C)(C)NC(=O)c2ccc(N3CC[C@H](O)C3)c(OCC3CC3)n2)no1
HCID71093530

未命名化合物

PROCEDURE

实验过程

The title compound was synthesized in analogy to Example 322b, using 5-bromo-6-cyclopropylmethoxy-pyridine-2-carboxylic acid [1-methyl-1-(5-methyl-[1,2,4]oxadiazol-3-yl)-ethyl]-amide (Example 322a) and (35)-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-pyrrolidine (CAN 207113-36-8) as starting materials. The protecting group was removed with tetrabutylammonium fluoride in THF; LC-MS (UV peak area/ESI) 100%, 402.2134 (M+H)+.

WORKUP

后处理

  1. customThe protecting group was removed with tetrabutylammonium fluoride in THF