HRID931713

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：Cc1ccc2c(-c3ccc(Cl)cc3)c([C@H](OC(C)(C)C)C(=O)O)c(Cl)cc2n1

HCID56644218

未命名化合物

结构：Cc1cc2ncccc2c(-c2ccc(Cl)cc2)c1[C@@H](CO)OC(C)(C)C

HCID66631592

未命名化合物

PRODUCTS

生成物

结构：Cc1cc2ncccc2c(-c2ccc(Cl)cc2)c1[C@H](OC(C)(C)C)C(=O)O

HCID56644220

未命名化合物

PROCEDURE

实验过程

(S)-2-tert-butoxy-2-(5-(4-chlorophenyl)-7-methylquinolin-6-yl)acetic acid (3L) was prepared following the procedure used to prepare compound 1L of Example 1, except that (S)-2-tert-butoxy-2-(5-(4-chlorophenyl)-7-methylquinolin-6-yl)ethanol (3K) was used instead of compound 1L. 1H-NMR 300 MHz, (CDCl3) δ 8.89-8.86 (m, 1H), 7.98 (s, 1H), 7.75-7.65 (m, 2H), 7.58-7.50 (m, 2H), 7.30-7.20 (m, 2H), 5.30 (s, 1H), 2.66 (s, 3H), 1.02 (s, 9H); LCMS-ESI+ (m/z): [M+H]+ calcd for C22H23ClNO3: 384.9. Found:384.1, 386.1.