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HRID931797

反应详情

EQUATION

反应方程式

HRID 931797 的结构方程式

REACTANTS

反应物

2
结构：Cc1cc2nc(CCc3ccccc3)ccc2c(-c2ccc(Cl)cc2)c1[C@@H](CO)OC(C)(C)C
HCID66631635

未命名化合物

结构：Cc1cc2nc(N3CCOCC3)ccc2c(-c2ccc(Cl)cc2)c1[C@@H](COC(=O)C(C)(C)C)OC(C)(C)C
HCID66631939

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cc2nc(CCc3ccccc3)ccc2c(-c2ccc(Cl)cc2)c1[C@H](OC(C)(C)C)C(=O)O
HCID56645258

未命名化合物

PROCEDURE

实验过程

(S)-2-tert-Butoxy-2-(5-(4-chlorophenyl)-7-methyl-2-phenethylquinolin-6-yl)acetic acid (4.8 mg) was prepared in a similar manner as compound (S)-2-tert-butoxy-2-(5-(4-chlorophenyl)-7-methyl-2-morpholinoquinolin-6-yl)acetic acid of Example 29 except using (S)-2-tert-butoxy-2-(5-(4-chlorophenyl)-7-methyl-2-phenethylquinolin-6-yl)ethanol instead of (S)-2-tert-butoxy-2-(5-(4-chlorophenyl)-7-methyl-2-morpholinoquinolin-6-yl)ethanol. 1H-NMR 400 MHz (CD3OD) δ 8.21 (d, J=8 Hz, 1 H), 7.93 (s, 1 H), 7.7-7.6 (m, 4 H), 7.37 (d, J=8 Hz, 1 H), 7.3-7.15 (m, 5 H), 5.24 (s, 1 H), 3.46 (d, J=7.6 Hz, 2 H), 3.18 (d, J=7.6 Hz, 2 H), 2.76 (s, 3 H), 0.96 (s, 9 H); LCMS-ESI+ (m/z): [M+H]+ calcd for C30H31ClNO3: 488.2. Found: 488.2.