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HRID987967

反应详情

EQUATION

反应方程式

HRID 987967 的结构方程式

REACTANTS

反应物

4
结构：N[C@@H](Cc1ccccc1)C(=O)O
HCID6140

L-Phenylalanine

C9H11NO2

结构：COc1ccc(S(=O)(=O)N(CC(C)C)[C@H](CO)CCCCNC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)N2CCOCC2)cc1
HCID513957

未命名化合物

结构：O=C(O)[C@H](Cc1cccc2ccccc12)NC(=O)N1CCOCC1
HCID12986165

未命名化合物

结构：O=C(O)[C@@H](NC(=O)N1CCOCC1)C(c1ccccc1)c1ccccc1
HCID12986168

未命名化合物

PRODUCTS

生成物

2
结构：CC(C)CN([C@H](CO)CCCCNC(=O)[C@@H](NC(=O)N1CCOCC1)C(c1ccccc1)c1ccccc1)S(=O)(=O)c1ccc(N)cc1
HCID513962

N-[(1S)-1-[[[(5S)-5-[[(4-Aminophenyl)sulfonyl](2-methylpropyl)amino]-6-hydroxyhexyl]amino]carbonyl]-2,2-diphenylethyl]-4-morpholinecarboxamide

C36H49N5O6S

结构：O=C(O)[C@@H](NC(=O)N1CCOCC1)C(c1ccccc1)c1ccccc1
HCID12986168

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from (1S)-4-amino-N-(5-amino-1-hydroxymethyl-pentyl)-N-isobutyl-benzenesulfonamide (XII) (example 28, step D) as described in general procedure B using (2S)-2-[(morpholine-4-carbonyl)-amino]-3,3-diphenyl-propionic acid. The (2S)-2-[(morpholine-4-carbonyl)-amino]-3,3-diphenyl-propionic acid derivative was prepared from L-diphenylalanine as described for the preparation of (2S)-2-[(morpholine-4-carbonyl)-amino]-3-naphthalen-1-yl-propionic acid (example 32, step A). The final product was obtained in 28% yield (14 mg).