二甲胺盐酸盐 (HCID 10473)

名称与标识

首选名称: Dimethylamine, hydrochloride
IUPAC: N-methylmethanamine;hydrochloride
中文名: 二甲胺盐酸盐
英文名: Dimethylamine hydrochloride
分子式: C2H8ClN
分子量: 81.54

名称与别名

Dimethylamine hydrochloride506-59-2Dimethylammonium chlorideDimethylamine, hydrochlorideHydrochloric acid dimethylamine7M4CWB6AOKRefChem:588486208-046-5N-Methylmethanamine hydrochlorideMethanamine, N-methyl-, hydrochlorideDIMETHYLAMINE HClMFCD00012477

展开更多名称

盐酸二甲胺二甲胺盐酸盐二甲胺鹽酸鹽二甲胺,盐酸盐盐酸氨基二甲烷二甲基胺氯化氫氯化氫二甲基胺二甲氨基盐酸盐达卡巴嗪杂质3盐酸二甲胺标准品METHANAMINE HYDROCHLORIDEDMAClMetformin impurity F CRSDiMethylaMine hydrochloridMetformin EP Impurity F HClJACS-506-59-2Dimethylamine hydrocImatinib EP Impurity I

C2H8ClNN,N-dimethylamine hydrochlorideDTXSID8027163N-methylmethanamine;hydrochlorideMethanamine, N-methyl-, hydrochloride (1:1)DIMETHYLAMINE-15-N HYDROCHLORIDEDimethyl amine hydrochloridedimethyl ammonium chloride

数据库标识

CAS: 506-59-2
PubChem CID: 10473
DTXSID: DTXSID8027163
ChEMBL: CHEMBL569461
UNII: 7M4CWB6AOK
EC Number: 208-046-5

性质

结构计算性质

极性表面积: 12 Å²
氢键供体: 2
氢键受体: 1
可旋转键: 0
重原子: 4
形式电荷: 0
复杂度: 2.8

实验与物化性质

Chemical ClassesNitrogen Compounds -> Amines, Aliphatic

Vapor Pressure0.000435 [mmHg]

Physical DescriptionDeliquescent solid; [Merck Index] White to off-white odorless solid; Hygroscopic; [Acros Organics MSDS]

物理化学性质

熔点: 170 · 170-173 °C(lit.)
沸点: 95.79 °C · 95.79°C (rough estimate)
堆积密度: 500 kg/m3 · 500kg/m3
密度: 0.8949 · 0.8949 (rough estimate)
蒸气压: 0.1 hPa · <0.1 hPa (25 °C)
折射率: 1.4202 · 1.4202 (estimate)
储存条件: 30 °C · Store below +30°C.
溶解度: 2 O: · H2O: soluble0.5g/10 mL
形态: Crystalline Powder or Crystals
颜色: White to off-white
PH值: 5 · 5 (100g/l, H2O, 20℃)
水溶解性: 3000 g/L · 3000 g/L (20 ºC)
敏感性: Hygroscopic
Merck: 14 · 14,3228
BRN: 3589311 · 3589311
稳定性: Stable. Incompatible with strong oxidizing agents.
InChI: 1S/C2H7N.ClH/c1-3-2;/h3H,1-2H3;1H
InChIKey: IQDGSYLLQPDQDV-UHFFFAOYSA-N
SMILES: Cl[H].CNC
LogP: -3.28 · -3.28
CAS 数据库: 506 · 506-59-2(CAS DataBase Reference)
EPA化学物质信息: Methanamine, N-methyl-, hydrochloride (506-59-2)

化学性质

白色叶状晶体。熔点171℃。易溶于水，溶于醇、氯仿，不溶于醚。具潮解性。

安全与法规

GHS分类

GHS Classification · 6 条

Warning

H302 (99.7%): Harmful if swallowed [Warning Acute toxicity, oral]

P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 363 reports by companies from 12 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Warning

H302: Harmful if swallowed [Warning Acute toxicity, oral]

危害信息

Regulatory Information · 3 条

Chemical: Methanamine, N-methyl-, hydrochloride

Status: Active Update: 17-09-2021 https://echa.europa.eu/registration-dossier/-/registered-dossier/13403

Dimethylammonium chloride: Does not have an individual approval but may be used under an appropriate group standard

Hazards SummaryAn irritant; Possible reproductive and fetal toxicant, based on animal studies; [Acros Organics MSDS] See Dimethylamine.

Hazard Classes and Categories · 2 条

Acute Tox. 4 (99.7%)

Acute toxicity (Oral) - Category 4

安全数据

F: 3-9
wgk: 1
tsca: TSCA listed
毒性: LD50 in mice (g/kg): 1.21 i.v., 2.00 s.c. (Hazard); LC50 in mice (ppm): 7650 (48 hr), 4725 (14 day); in rats (ppm): 4540 (6 hr) (Steinhagen)
RTECS号: IQ0220000
存储类别: 11 - Combustible Solids
安全说明: 26-36/37-37/39-36
海关编码: 29211190
危险品标志: Xn
危险性类别: Acute Tox. 4 OralEye Irrit. 2Skin Irrit. 2
危险类别码: 22-36/37/38

化学与工业

用途与制造

Uses · 2 条

Used as a rubber accelerator and in leather tanning; Also used to make detergents and as a boll weevil attractant; [Merck Index] Used as a catalyst for polymerization reactions, epoxy monomer for paints-coatings-thinners and polymers, to make fine and large scale chemicals, pharmaceuticals, and pesticides, and in electricity-steam-gas-water supply and sewage treatment; [ExPub: ECHA REACH Registrations]

Painting (Pigments, Binders, and Biocides) [Category: Paint]

General Manufacturing InformationMethanamine, N-methyl-, hydrochloride (1:1): ACTIVE

应用领域 · 5 条

用途二甲胺盐酸盐是有机合成的原料，还用作乙酰化分析的催化剂和镁试剂和二甲胺水溶液的制备。二甲胺盐酸盐去氧化能力很强，腐蚀性强，所以常用于清洗型助焊剂。

用途1.活性较高，能减少表面张力，使焊料与被焊金属相互润湿，增强助焊能力；2.有机分析试剂，乙酰化分析时用作催化剂，也用于有机合成和二甲胺水溶液的制备。

用途二甲胺盐酸盐是有机合成的原料，还用作乙酰化分析的催化剂和镁试剂。

用途乙酰化分析时用作催化剂，也用于有机合成和二甲胺水溶液的制备

用途用作制药的原料

制备方法

生产方法由二甲胺与盐酸成盐而得。将盐酸缓缓滴入二甲胺中，30%的盐酸用量约为40%二甲胺的1.1倍，滴入速度以温度不超过15℃，pH=7-8为限。反应结束后，加活性炭脱色，过滤，滤液用盐酸调节至pH=3-4，减压蒸水至尽，得二甲胺盐酸盐。

试剂价格

30067026 · 100G: 二甲胺，盐酸盐(XZ)dimethylamine hydrochloride;metformin impurity f — 48元
S6197 · 25mg: 二甲胺盐酸盐Dimethylamine hydrochloride — 794.5元

供应商50 家

国药集团化学试剂有限公司86-21-63210123 · [email protected]

衢州润东化工有限公司0570-8789886 18892685668 · [email protected]

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

T&W GROUP021-61551611 13296011611 · [email protected]

爱斯特（成都）生物制药股份有限公司+86-28-85122536 85324413 · [email protected]

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二甲胺盐酸盐

基本信息