4-氨基哌啶-3-甲醇

4-Aminopyridine-3-methanol

HCID 10796739CAS 138116-34-4

基本信息

标准SMILES: Nc1ccncc1CO
InChIKey: WNBVEYMTVDMSFZ-UHFFFAOYSA-N
分子式: C6H8N2O
平均分子量: 124.14 g/mol
单同位素质量: 124.06366288

概述

4-aminopyridine-3-methanol is an aminopyridine that is 4-aminopyridine which is substituted by a hydroxymethyl group at position 3. It is a potassium channel blocker which restores axonal conduction after spinal cord injury. It has a role as a potassium channel blocker. It is an aromatic primary alcohol, an aromatic amine and an aminopyridine. It is functionally related to a 4-aminopyridine.

名称与标识

首选名称: 4-Aminopyridine-3-methanol
IUPAC: (4-amino-3-pyridinyl)methanol
中文名: 4-氨基哌啶-3-甲醇
英文名: (4-Amino-pyridin-3-yl)-methanol
分子式: C6H8N2O
分子量: 124.14

名称与别名

4-Aminopyridine-3-methanolCHEBI:149772RefChem:978814-AP-3-Me0H(4-aminopyridin-3-yl)methanol138116-34-4(4-Amino-pyridin-3-yl)-methanol3-Pyridinemethanol, 4-amino-4-AMINO-3-PYRIDINEMETHANOLMFCD062030664-Amino-3-hydroxymethylpyridine(4-amino-3-pyridyl)methanol

展开更多名称

4-氨基吡啶-3-甲醇4-氨基哌啶-3-甲醇4-氨基-3-吡啶甲醇4-氨基-3-羟甲基吡啶(4-氨基吡啶-3-基)甲醇中文名:?4-氨基哌啶-3-甲醇英文名:?(4-AMINOPYRIDIN-3-YL)METHANOLCAS号:138116-34-4RARECHEM AL BD 13863-AMINO-4-PYRIDINE METHANOL4-AMINO-3-PYRIDINE METHANOL4-Aminopyridine-3-methanol ,97%3-Pyridinemethanol,4-amino-(9CI)(4-AMINO-PYRIDIN-3-YL)-METHANOL ISO 9001：2015 REACH

4-AP-3-MeOHSCHEMBL1930789SCHEMBL2067171SCHEMBL2642427SCHEMBL29964442DTXSID10444916WNBVEYMTVDMSFZ-UHFFFAOYSA-N(4-amino-3-pyridyl)methan-1-ol

数据库标识

CAS: 138116-34-4
PubChem CID: 10796739
DTXSID: DTXSID10444916
ChEBI: CHEBI:149772
EC Number: 681-133-7

性质

结构计算性质

XLogP: -0.2
极性表面积: 59.1 Å²
氢键供体: 2
氢键受体: 3
可旋转键: 1
重原子: 9
形式电荷: 0
复杂度: 87.1

物理化学性质

熔点: 167 · 167-169℃
沸点: 367.2 · 367.2±27.0 °C(Predicted)
密度: 1.257 · 1.257±0.06 g/cm3(Predicted)
储存条件: 2 · under inert gas (nitrogen or Argon) at 2–8 °C
溶解度: DMSO (Slightly), Methanol (Slightly)
形态: Solid
酸度系数(pKa): 13.54 · 13.54±0.10(Predicted)
颜色: Pale Brown
水溶解性: Slightly soluble in water.
敏感性: Air Sensitive
稳定性: Air Sensitive
InChI: 1S/C6H8N2O/c7-6-1-2-8-3-5(6)4-9/h1-3,9H,4H2,(H2,7,8)
InChIKey: WNBVEYMTVDMSFZ-UHFFFAOYSA-N
SMILES: Nc1ccncc1CO

安全与法规

GHS分类

GHS Classification · 4 条

Danger

H300 (16.7%): Fatal if swallowed [Danger Acute toxicity, oral]

P261, P264, P264+P265, P270, P271, P280, P301+P316, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 6 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

危害信息

Hazard Classes and CategoriesAcute Tox. 2 (16.7%)

安全数据

wgk: 3
RTECS号: US1750000
危险等级: IRRITANT
存储类别: 6.1A - Combustible acute toxic Cat. 1 and 2very toxic hazardous materials
安全说明: 26-36/37/39-45-37
海关编码: 29333990
危险品标志: Xi,T+
危险性类别: Acute Tox. 2 OralAcute Tox. 3 DermalAcute Tox. 3 InhalationAquatic Chronic 2Eye Dam. 1Skin Corr. 1B
危险类别码: 28-36/37/38
危险品运输编号: UN 2811 6.1 / PGII

化学与工业

上下游产品信息

上游原料

4-氨基烟酸甲酯四氢呋喃氢化铝锂

下游产品

(3-(羟甲基)吡啶-4-基)氨基甲酸叔丁酯

试剂价格

XW0213811634402 · 250MG: 4-氨基吡啶-3-甲醇 — 129元
XW0213811634401 · 100MG: 4-氨基吡啶-3-甲醇 — 68元

供应商50 家

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

陕西缔都新材料有限公司81124267 17392282731 · [email protected]

毕佳索（上海毕得医药科技股份有限公司）400-6005915 · [email protected]

上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]

Suzhou ARTK Medchem Co., Ltd.+86-18168183658 · [email protected]

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