氨基三亚甲基膦酸 (HCID 16698)

概述

[Nitrilotris(methylene)]trisphosphonic acid is a phosphonoacetic acid.

名称与标识

首选名称: Aminotrimethylene phosphonic acid
IUPAC: [bis(phosphonomethyl)amino]methylphosphonic acid
中文名: 氨基三亚甲基膦酸
英文名: Amino tris(methylene phosphonic acid)
分子式: C3H12NO9P3
分子量: 299.05

名称与别名

6419-19-8Tris(phosphonomethyl)amineAminotrimethylene phosphonic acidFerrofos 509Dequest 2000Dowell L 37Aminotris(methanephosphonic acid)Nitrilotrimethylphosphonic acidAminotri(methylene phosphonic acid)Aminotris(methylphosphonic acid)Aminotri(methylenephosphonic acid)Aminotri(methylphosphonic acid)

展开更多名称

氨基三甲基磷酸氨基三甲叉膦酸氨三亚甲基膦酸氨基三甲叉麟酸氨基三甲叉瞵酸氨基三亚甲基膦酸氮基三亚甲基磷酸氨三亚甲基三磷酸次氨基三甲叉瞵酸氨基三亞甲基磷酸ATMPAMINO TRIMETHYLENE PHOSPHONIC ACID (ATMP)ATMPAntpoNitriLNITRILOTRI(METHYLPHOSPHONIC ACID)(nitrilo

Nitrilotrimethanephosphonic acidNitrilotrimethylenephosphonic acidAminotris(methylenephosphonic acid)Amino, tris(methylene phosphonic acid)Nitrilotrimethylenetris(phosphonic acid)NITRILOTRIS(METHYLPHOSPHONIC ACID)(Nitrilotris(methylene))trisphosphonic acidEINECS 229-146-5

数据库标识

CAS: 20592-85-2、6419-19-8
PubChem CID: 16698
DTXSID: DTXSID2027624
ChEMBL: CHEMBL260191
ChEBI: CHEBI:168957
UNII: 1Y702GD0FG
EC Number: 229-146-5、243-900-0
Nikkaji: J56.127D

性质

结构计算性质

XLogP: -7.2
极性表面积: 176 Å²
氢键供体: 6
氢键受体: 10
可旋转键: 6
重原子: 16
形式电荷: 0
复杂度: 305

实验与物化性质

Chemical ClassesOther Classes -> Phosphate Compounds

CosmeticsChelating

SpringerMaterials PropertiesCrystal structure

LogP-3.53

Density1.33 @ 20°C

Solubility1000 mg/mL at 25 °C

物理化学性质

熔点: 215 °C · ~215 °C (dec.)
沸点: 746.2 · 746.2±70.0 °C(Predicted)
密度: 1.3 g/mL · 1.3 g/mL at 25 °C
蒸气压: 0 Pa · 0Pa at 25℃
储存条件: Sealed in dry,Room Temperature
溶解度: Water (Slightly, Heated)
酸度系数(pKa): 0.56 · 0.56±0.10(Predicted)
形态: Solid
颜色: White
PH值: 0.46 · 0.46
水溶解性: 500 g/L · 500g/L at 20℃
BRN: 1715724 · 1715724
稳定性: Stable. Incompatible with bases, strong oxidizing agents.
化妆品成分功效: CHELATING
InChI: 1S/C3H12NO9P3/c5-14(6,7)1-4(2-15(8,9)10)3-16(11,12)13/h1-3H2,(H2,5,6,7)(H2,8,9,10)(H2,11,12,13)
InChIKey: YDONNITUKPKTIG-UHFFFAOYSA-N
SMILES: OP(O)(=O)CN(CP(O)(O)=O)CP(O)(O)=O
LogP: -3.5 · -3.5
CAS 数据库: 6419 · 6419-19-8(CAS DataBase Reference)
EPA化学物质信息: Aminotri(methylene phosphonic acid) (6419-19-8)

安全与法规

GHS分类

GHS Classification · 6 条

This chemical does not meet GHS hazard criteria for 8.2% (66 of 802) of reports.

Warning

H290 (48.4%): May be corrosive to metals [Warning Corrosive to Metals]

P234, P264, P264+P265, P280, P302+P352, P305+P351+P338, P321, P332+P317, P337+P317, P362+P364, P390, and P406 (click each P-code to see the statement)

Aggregated GHS information provided per 802 reports by companies from 29 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

This chemical does not meet GHS hazard criteria for 96.5% (305 of 316) of all reports.

危害信息

Regulatory Information · 6 条

Chemical: Phosphonic acid, P,Pâ²,Pâ²â²-[nitrilotris(methylene)]tris-

Phosphonic acid, P,P',P''-[nitrilotris(methylene)]tris-, sodium salt (1:?) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Phosphonic acid, P,P',P''-[nitrilotris(methylene)]tris-, sodium salt (1:?) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Phosphonic acid, P,P',P''-[nitrilotris(methylene)]tris- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Phosphonic acid, P,P',P''-[nitrilotris(methylene)]tris- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 24-02-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/15198

Status: Active Update: 18-04-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/14507

Aminotri(methylenephosphonic acid): Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - Phosphonic acid, [nitrilotris(methylene)]tris-: Human health tier I assessment

Hazards SummaryAn eye irritant; [MSDSonline] No adverse effects reported in workers except irritation in >20 years of use; [AIHA]

EPA Safer ChemicalChemical: Aminotrimethylene phosphonic acid

Hazard Classes and Categories · 2 条

Not Classified

Met. Corr. 1 (48.4%)

安全与防护

Protective Action Criteria (PAC) · 3 条

30 [mg/m3]

69 [mg/m3]

420 [mg/m3]

安全数据

F: 3-9
wgk: 1
tsca: TSCA listed
RTECS号: SZ9860000
包装类别: III
危险等级: 8
存储类别: 8A - Combustible corrosive hazardous materials
安全说明: 26-45-36/37/39-25-44-36
海关编码: 29319090
危险品标志: Xi,C
危险性类别: Met. Corr. 1
危险类别码: 36-34-35
危险品运输编号: 3265

化学与工业

药理信息

Cellular LocationsCytoplasm

用途与制造

Uses · 2 条

Used mainly as a deflocculant and sequestrant (chelating or complexing agent) in industrial water treatment; Also used in cleaners and in stabilizers (peroxide solutions to bleach cotton, linen, jute, rayon, and paper); [CHEMINFO]

Pulp and Paper Processing [Category: Industry]

U.S. Production · 2 条

2023: 2,500,000 - <4,000,000 lb

2023: 4,000,000 - <5,500,000 lb

Consumer Uses · 2 条

Chelating agent

Industry Uses · 2 条

Lubricating agent

Cleaning agent

Household ProductsInformation on 8 consumer products that contain Aminotrimethylene Phosphonic Acid in the following categories is provided:

Use Classification · 3 条

EPA Safer Chemical Functional Use Classes -> Oxidants and Oxidant Stabilizers

Safer Chemical Classes -> Yellow triangle - The chemical has met Safer Choice Criteria for its functional ingredient-class, but has some hazard profile issues

Cosmetics -> Chelating

应用领域 · 6 条

简介氯基三甲叉膦酸又叫氨基三亚甲基膦酸（ATMP），具有良好的螯合、低限抑制及晶格畸变作用。可阻止水中成垢盐类形成水垢，特别是碳酸钙垢的形成。氨基三亚甲基膦酸在水中化学性质稳定，不易水解。在水中浓度较高时，有良好的缓蚀效果。

应用氯基三甲叉膦酸用于火力发电厂、炼油厂的循环冷却水、油田回注水系统。可以起到减少金属设备或管路腐蚀和结垢的作用。氨基三亚甲基膦酸在纺织印染等行业用作金属离子螯合剂，也可用于金属表面处理剂等。

用途ATMP在水中化学性质稳定，不易水解。在水中浓度较高时，氨基三亚甲基膦酸有良好的缓蚀效果。ATMP用于火力发电厂、炼油厂的循环冷却水、油田回注水系统。氨基三亚甲基膦酸可以起到减少金属设备或管路腐蚀和结垢的作用。ATM在纺织印染等行业用作金属离子螯合剂，也可用于金属表面处理剂等。固体为结晶性粉末，易溶于水，易吸潮，易于运输和使用，尤其适用于冬季严寒地区。由于氨基三亚甲基膦酸ATMP纯度较高，可用作纺织印染行业的金属鳌合剂及金属表面处理剂。 ATMP具有良好的整合、低限抑制及晶格畸变作用。可阻止水中成垢盐类形成水垢，特别是碳酸钙垢的形成。ATMP在水中化学性质稳定，不易水解。在水中浓度较高时，有良好的缓蚀效果ATMP用于火力发电厂、炼油厂的循环冷却水、油田回注水系统。可以起到减少金属设备或管路腐蚀和结垢的作用。ATMP在纺织印染等行业用作金属离子螯合剂，也可用于金属表面处理剂等。ATMP固体为结晶性粉末，易溶于水，易吸潮，易于运输和使用，尤其适用于冬季严寒地区。由于纯度较高，可用作纺织印染行业的金属鳌合剂及金属表面处理剂。

用途冷却水系统、输油管线及锅炉的防垢，它可作为高硬度，高矿化度等水质的恶劣的油管线的阻垢剂。

用途用于冷却水、锅炉水、油田水处理的阻垢剂和缓蚀剂

用途用于火力发电厂、炼油厂的循环冷

制备方法

制备(1)将15g黄磷打入经氮气除氧的密闭反应釜中；(2)加热至45℃后向反应釜内通入少量的高纯氧，在不充足的氧气下不完全燃烧，在密闭反应釜得到三氧化二磷(P2O3)；(3)向密闭反应釜中加入90g水、40g氯化铵，在20℃搅拌混合60min，搅拌后再滴加100g质量分数为37％甲醛溶液，滴加后加热至50℃，反应2h，然后再以1.5℃/min升温至110℃，反应1h；(4)反应完全后控制温度125℃进行蒸馏，待无物料蒸出时即可得氯基三甲叉膦酸。

上下游产品信息

上游原料

甲醛水溶液三氯化磷氯化铵

下游产品

壳聚糖

试剂价格

N0474 · 25ML: 次氮基三(亚甲基膦酸)(约50%的水溶液,约2.2mol/L)Nitrilotris(methylenephosphonic Acid) (ca. 50% in Water, ca. 2.2mol/L) — 120元
N0474 · 100ML: 氨基三亚甲基膦酸Nitrilotris(methylenephosphonic Acid) (ca. 50% in Water, ca. 2.2mol/L) — 250元

供应商50 家

国药集团化学试剂有限公司86-21-63210123 · [email protected]

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

河北创海生物科技有限公司+86-86-13131129325 · [email protected]

Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]

关联笔记

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氨基三亚甲基膦酸

基本信息

概述