palladium acetate

palladium(II) acetate

HCID 167845CAS 19807-27-3

基本信息

标准SMILES: CC(=O)[O-].CC(=O)[O-].[Pd+2]
InChIKey: YJVFFLUZDVXJQI-UHFFFAOYSA-L
分子式: C4H6O4Pd
平均分子量: 224.51 g/mol
单同位素质量: 223.93009467

概述

Palladium acetate is a chemical compound of palladium. It is used as a catalyst for many organic reactions and as a precursor to other palladium(II) compounds. Palladium is a chemical element with the chemical symbol Pd and an atomic number of 46. It is found as a free metal alloyed with gold and other platinum group metals and in the rare minerals cooperite and polarite. (L794, L804)

名称与标识

首选名称: palladium(II) acetate
IUPAC: palladium(2+) diacetate
中文名: palladium acetate
英文名: palladium acetate
分子式: C2H4O2.xPd
分子量: 0

名称与别名

Palladium(II) acetate3375-31-3Palladium diacetateDiacetatopalladiumDiacetoxypalladiumBis(acetato)palladiumBisacetylpalladiumPalladous acetatePalladium(2+) acetatePd(OAc)2Acetic acid palladium saltAcetic acid, palladium salt

展开更多名称

乙酸钯(Ⅱ)二醋酸钯(Ⅱ)Einecs 243-333-9Acetic acid, palladium salt (1:)

0LTG3460Y5DTXSID10890575(ACETYLOXY)PALLADIO ACETATERefChem:169636DTXCID601030789222-164-4243-333-9Palladium acetate

数据库标识

CAS: 19807-27-3、3375-31-3
PubChem CID: 167845
DTXSID: DTXSID10890575
UNII: 0LTG3460Y5
EC Number: 222-164-4、243-333-9
Nikkaji: J10.642I

性质

结构计算性质

极性表面积: 80.3 Å²
氢键供体: 0
氢键受体: 4
可旋转键: 0
重原子: 9
形式电荷: 0
复杂度: 25.5

实验与物化性质

Chemical ClassesMetals -> Organic Acids, Metal Salts

Physical DescriptionReddish-brown solid; Insoluble in water; [Hawley] Powder; [MSDSonline]

物理化学性质

熔点: 205 ° · 205° (dec)
EPA化学物质信息: Acetic acid, palladium salt (19807-27-3)

安全与法规

GHS分类

GHS Classification · 4 条

Danger

H302 (11.3%): Harmful if swallowed [Warning Acute toxicity, oral]

P261, P264, P264+P265, P270, P272, P273, P280, P301+P317, P302+P352, P305+P354+P338, P317, P321, P330, P333+P317, P362+P364, P391, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 265 reports by companies from 18 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

危害信息

Regulatory Information · 3 条

Chemical: Acetic acid, palladium(2+) salt

Status: Active Update: 21-02-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/17957

Palladium (II) acetate: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - Acetic acid, palladium(2+) salt: Environment tier I assessment

Hazards SummaryCorrosive to eyes; [eChemPortal: ERMA] An irritant; May cause serious injury to eyes; [MSDSonline]

Hazard Classes and CategoriesAcute Tox. 4 (11.3%)

毒理信息

Health EffectsContact with palladium may cause palladium sensitivity and allergy. Animal studies have shown that palladium may damage the liver and kidney. (L798)

Toxicity Summary · 1 条

Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ions can disturb cellular equilibria, replace other essential ions, and interact with functional groups of macromolecules, such as proteins or DNA. Palladium complexes binding to DNA and RNA leads to strand breakage. Palladium ions are able to inhibit most major cellular functions, including DNA and RNA synthesis. Palladium compounds have been shown to bind to and inhibit various enzymes, including creatine kinase and prolyl hydroxylase. (L798)

Signs and SymptomsSkin contact with palladium may cause contact dermatitis, erythema, and oedema. (L798)

Carcinogen ClassificationNo indication of carcinogenicity to humans (not listed by IARC).

安全数据

tsca: TSCA listed

化学与工业

药理信息

Metabolism/Metabolites · 1 条

Palladium may be absorbed through oral, dermal, and inhalation exposure. Once in the body it distributes to the kidney, liver, spleen, lymph nodes, adrenal gland, lung and bone. Palladium's ability to form complexes allows it the bind to amino acids, proteins, DNA, and other macromolecules. Palladium and its metabolites are excreted in the urine and faeces. (A21)