二(三叔丁基膦)钯

Bis(tri-tert-butylphosphine)palladium(0)

HCID 2734558CAS 53199-31-8

基本信息

标准SMILES
CC(C)(C)P(C(C)(C)C)C(C)(C)C.CC(C)(C)P(C(C)(C)C)C(C)(C)C.[Pd]
InChIKey
MXQOYLRVSVOCQT-UHFFFAOYSA-N
分子式
C24H54P2Pd
平均分子量
511.1 g/mol
单同位素质量
510.27356

名称与标识

首选名称
Bis(tri-tert-butylphosphine)palladium(0)
IUPAC
palladium;bis(tritert-butylphosphane)
中文名
二(三叔丁基膦)钯
英文名
Bis(tri-tert-butylphosphine)palladium(0)
分子式
C24H56P2Pd
分子量
513.08

名称与别名

53199-31-8Bis(tri-tert-butylphosphine)palladium(0)DTXSID80370359RefChem:329913DTXCID10321394640-284-9BIS(TRI-TERT-BUTYLPHOSPHINE)PALLADIUMpalladium;tritert-butylphosphaneBis(tri-t-butylphosphine)palladium(0)bis(tri-tert-butylphosphane) palladiumMFCD03094580PD(T-BU3P)2
展开更多名称
(三叔丁基膦)钯双(三叔丁基膦)钯双(三特丁基膦)钯二(三叔丁基膦)钯双(三叔丁基膦)化钯二(三-T-丁基膦)钯二(三叔丁基膦)钯 1G双(三叔丁基膦)钯(0)双(三叔丁基膦)合钯(0)二(三-T-丁基膦)钯(0)Pd(P(t-Bu)3)2Bis[tris(tert-butyl)phosphine]palladiumBis[tris(tert-butyl)phosphine]palladium, 20.9% PdBIS(TRI-TERT-BUTYLPHOSPHINE)PALLADIUM (0)bis(tri-tert-butylphosphoranyl)palladiumBis(t
Bis(tri-t-butylphosphine)palladium (0)pd(p(tbu)3)2BIS(TRI-T-BUTYLPHOSPHINE)PALLADIUMC24H54P2PdPalladium, bis[tris(1,1-dimethylethyl)phosphine]-SCHEMBL43560SCHEMBL30986582STR08646

数据库标识

CAS
53199-31-8
PubChem CID
2734558
DTXSID
DTXSID80370359
EC Number
640-284-9

性质

结构计算性质

极性表面积
0 Ų
氢键供体
0
氢键受体
0
可旋转键
6
重原子
27

物理化学性质

熔点
300 °C · >300 °C
储存条件
-20 °C · -20°C
形态
Crystals
颜色
Off-white to orange-brown
水溶解性
insoluble
敏感性
Light, Air & Moisture Sensitive

化学性质

二(三叔丁基膦)钯在常温常压下稳定,是一种非常有效的钯催化剂。由于叔丁基基团的加入,二(三叔丁基膦)钯比其他膦配体更具有热稳定性,可在高温条件下使用。二(三叔丁基膦)钯作为催化剂的反应活性受到配体的影响很大,一般来说,较大的配体与钯离子的作用更强,使得催化活性降低。二(三叔丁基膦)钯的叔丁基基团较大,使得配体与钯离子的相互作用减弱,反应活性较高。二(三叔丁基膦)钯在很多有机溶剂中都易于溶解,如甲苯、二甲基甲酰胺(DMF)和乙腈等。

安全与法规

GHS分类

GHS Classification · 5 条

Danger

H228 (69.7%): Flammable solid [Danger Flammable solids];H251 (66.7%): Self-heating; may catch fire [Danger Self-heating substances and mixtures];H302+H312+H332 (66.7%): Harmful if swallowed, in contact with skin or if inhaled [Warning Acute toxicity, oral; acute toxicity, dermal; acute toxicity, inhalation];H302 (75.8%): Harmful if swallowed [Warning Acute toxicity, oral];H312 (75.8%): Harmful in contact with skin [Warning Acute toxicity, dermal];H315 (97%): Causes skin irritation [Warning Skin corrosion/irritation];H317 (66.7%): May cause an allergic skin reaction [Warning Sensitization, Skin];H319 (97%): Causes serious eye irritation [Warning Serious eye damage/eye irritation];H332 (75.8%): Harmful if inhaled [Warning Acute toxicity, inhalation];H335 (27.3%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation];H400 (66.7%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard];H410 (66.7%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]

P210, P235, P240, P241, P261, P264, P264+P265, P270, P271, P272, P273, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P370+P378, P391, P403+P233, P405, P407, P410, P413, P420, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 33 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

危害信息

Hazard Classes and CategoriesFlam. Sol. 1 (69.7%);Self-heat. 1 (66.7%);Acute Tox. 4 (75.8%);Acute Tox. 4 (75.8%);Skin Irrit. 2 (97%);Skin Sens. 1A (66.7%);Eye Irrit. 2 (97%);Acute Tox. 4 (75.8%);STOT SE 3 (27.3%);Aquatic Acute 1 (66.7%);Aquatic Chronic 1 (66.7%)

安全数据

wgk
3
tsca
No
存储类别
11 - Combustible Solids
安全说明
24/25
海关编码
28439000
危险品标志
Xi

化学与工业

应用领域

应用二(三叔丁基膦)钯是一种常用的金属钯络合物,在有机合成化学中常用作偶联反应的催化剂,其具有较大的位阻和丰富的电子密度。由于其催化性能的优异,二(三叔丁基膦)钯已经被广泛应用于药物合成、天然产物合成、有机合成。

用途作为催化剂,用于Suzuki、Kumada、Negishi, Buchwald等偶联反应中

试剂价格

HY-W010772 · 250 mg
二(三叔丁基膦)钯Bis(tri-tert-butylphosphine)palladium(0) — 240元
HY-W010772 · 500 mg
二(三叔丁基膦)钯Bis(tri-tert-butylphosphine)palladium(0) — 384元

供应商50 家

北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
Baoji Guokang Healthchem co.,ltd+8615604608665 15604608665 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]

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