基本信息
- 标准SMILES
OC[C@H]1O[C@@](CO)(O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@@H]1O- InChIKey
CZMRCDWAGMRECN-UGDNZRGBSA-N- 分子式
- C12H22O11
- 平均分子量
- 342.3 g/mol
- 单同位素质量
- 342.11621152
概述
Sucrose appears as white odorless crystalline or powdery solid. Denser than water.
名称与标识
- 首选名称
- Sucrose
- IUPAC
- (2R,3R,4S,5S,6R)-2-[(2S,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
- 中文名
- 蔗糖
- 英文名
- Sucrose
- 分子式
- C12H22O11
- 分子量
- 342.3
名称与别名
展开更多名称
数据库标识
- CAS
57-50-1、92004-84-7- PubChem CID
- 5988
- DTXSID
DTXSID2021288- ChEMBL
CHEMBL253582- ChEBI
CHEBI:17992- UNII
- C151H8M554
- EC Number
- 200-334-9、618-806-1
- Nikkaji
- J4.581K
性质
结构计算性质
- XLogP
- -3.7
- 极性表面积
- 190 Ų
- 氢键供体
- 8
- 氢键受体
- 11
- 可旋转键
- 5
- 重原子
- 23
- 形式电荷
- 0
- 复杂度
- 395
实验与物化性质
Cosmetics
Cosmetic ingredients (Sucrose) -> CIR (Cosmetic Ingredient Review)
Soothing; Humectant; Skin conditioning
Pesticides
Agrochemicals -> Pesticide active substances
Active substance -> EU Pesticides database: Approved
LogP
log Kow = -3.70
-3.70
-3.67
-2.7
Odor
Characteristic caramel
... Odorless ... [Note: May have a characteristic caramel odor when heated].
Density
1.59 at 68 °F (USCG, 1999) - Denser than water; will sink
1.5805 g/cu cm @ 17 °C
1.6 g/cm³
1.59
1.59
Color/Form
Monoclinic sphenoidal crystals, crystalline masses, blocks, or powder
Hard, white ... crystals, lumps, or powder ...
物理化学性质
- 熔点
- 185 · 185-187 °C (lit.)
- 比旋光度
- 67 · 67 º (c=26, in water 25 ºC)
- 沸点
- 397.76 °C · 397.76°C (rough estimate)
- 堆积密度
- 800 · 800-950kg/m3
- 密度
- 1.5805 · 1.5805
- 折射率
- 66.5 ° · 66.5 ° (C=26, H2O)
- 闪点
- 93.3 °C · 93.3°C
- 储存条件
- Inert atmosphere,Room Temperature
- 溶解度
- 2 O: · H2O: 500 mg/mL
- 形态
- Liquid
- 酸度系数(pKa)
- 12.7 · 12.7(at 25℃)
- 颜色
- White
- PH值
- 5 · 5.0-7.0 (25℃, 1M in H2O)
- 酸碱指示剂变色ph值范围
- 5.5 · 5.5 - 7 at 342 g/l at 25 °C
- 气味 (Odor)
- Odorless
- 生物来源
- sugar cane
- 水溶解性
- 1970 g/L · 1970 g/L (15 ºC)
- 最大波长(λmax)
- 260 nm · λ: 260 nm Amax: 0.11λ: 280 nm Amax: 0.08
- Merck
- 14 · 14,8881
- BRN
- 90825 · 90825
- 介电常数
- 3.3 · 3.3(Ambient)
- 暴露限值
- 10 mg/m3OSHA:PEL-TWA · ACGIH:TLV-TWA 10 mg/m3OSHA:PEL-TWA 15 mg/m3 (total dust),5 mg/m3 (respirable fraction)NIOSH:REL-TWA 10 mg/m3 (total dust),5 mg/m3 (respirable fraction)
- 稳定性
- Stable. Combustible. Incompatible with strong oxidizing agents. Hydrolyzed by dilute acids and by invertase.
- 化妆品成分功效
- HUMECTANTSKIN CONDITIONINGSOOTHING
- InChI
- 1S/C12H22O11/c13-1-4-6(16)8(18)9(19)11(21-4)23-12(3-15)10(20)7(17)5(2-14)22-12/h4-11,13-20H,1-3H2/t4-,5-,6-,7-,8+,9-,10+,11-,12+/m1/s1
- InChIKey
- CZMRCDWAGMRECN-UGDNZRGBSA-N
- SMILES
- OC[C@H]1O[C@H](O[C@]2(CO)O[C@H](CO)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O
- LogP
- -4.492 · -4.492 (est)
- CAS 数据库
- 57 · 57-50-1(CAS DataBase Reference)
- NIST化学物质信息
- Sucrose(57-50-1)
- EPA化学物质信息
- Sucrose (57-50-1)
- Absorption
- 0.1 at · ≤0.100 at 280nm≤0.120 at 260nm
化学性质
白色结晶性无臭固体,有甜味。相对密度(d425)1.587,熔点170~186℃(分解)。易溶于水,不溶于乙醚。
安全与法规
GHS分类
GHS Classification
This chemical does not meet GHS hazard criteria for 95.7% (423 of 442) of all reports.
Not Classified
Aggregated GHS information provided per 442 reports by companies from 8 notifications to the ECHA C&L Inventory.
危害信息
Regulatory Information
Chemical: .alpha.-D-Glucopyranoside, .beta.-D-fructofuranosyl
.alpha.-D-Glucopyranoside, .beta.-D-fructofuranosyl is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of .alpha.-D-Glucopyranoside, .beta.-D-fructofuranosyl are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
Reg. (EU) No 916/2014
Sucrose: Does not have an individual approval but may be used under an appropriate group standard
Fire Hazards
Special Hazards of Combustion Products: Irritating fumes may form in fires.
Combustible. Finely dispersed particles form explosive mixtures in air.
FIFRA Requirements
Residues of sucrose are exempted from the requirement of a tolerance when used as a solid diluent, carrier or safener in accordance with good agricultural practices as inert (or occasionally active) ingredients in pesticide formulations applied to growing crops or to raw agricultural commodities after harvest.
Sucrose is exempted from the requirement of a tolerance when used as a solid diluent or carrier in accordance with good agricultural practice as inert (or occasionally active) ingredients in pesticide formulations applied to animals.
OSHA Standards
Permissible Exposure Limit: Table Z-1 8-hr Time Weighted Avg: 15 mg/cu m. /Total dust/
Permissible Exposure Limit: Table Z-1 8-hr Time Weighted Avg: 5 mg/cu m. /Respirable fraction/
Reactivity Profile
SUCROSE is a reducing agent. Can react explosively with oxidizing agents such as chlorates and perchlorates. Is hydrolyzed by dilute acids and by invertase (a yeast enzyme) (NTP, 1992). Chars rapidly and exothermically when mixed with concentrated sulfuric acid.
安全与防护
Fire Fighting
Fire Extinguishing Agents: Water (USCG, 1999)
Use water spray, powder, alcohol-resistant foam, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water.
First Aid Measures
Fresh air, rest.
Rinse skin with plenty of water or shower.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
First Aid
EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. If symptoms (such as redness or irritation) develop, immediately transport the victim to a hospital.
(General first aid procedures)
Nonfire Spill Response
SMALL SPILLS AND LEAKAGE: If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.
Disposal Methods
SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.
毒理信息
Exposure Routes
The substance can be absorbed into the body by inhalation and by ingestion.
inhalation, skin and/or eye contact
Signs and Symptoms
Cough.
Redness. Roughness.
Redness.
irritation eyes, skin, upper respiratory system; cough
Natural Pollution Sources
Occurs in low percentages in honey and maple sap
Sugar cane contains from 15-20% and sugar beet from 10-17% sucrose
The quantity of sucrose synthesized by all plants on earth is estimated to be 150X10+9 t/a.
Human Toxicity Excerpts
Liquid medicines, particularly those intended for children, often formulated as syrups, usually based on sucrose. Total sugar content may be up to 80% (w/v). Complicated diabetes management. Increased dental caries especially in chronically sick children (eg, asthmatics or epileptics) who frequently take liquid medicine.
Sucrose is reported to be capable of producing dermatoses in bakers, candy makers, and related occupations. It is well established that uncontrolled glucose conc in maternal blood are associated with elevated embryonic and fetal death and increased neonatal morbidity and mortality.
Non-Human Toxicity Excerpts
EVIDENCE EXISTS THAT HIGHLY CONCN SOLN ARE LETHAL TO NEMATODES IN SOIL.
DIFFUSE PATHOLOGICAL CHANGES /IN POISONED ANIMALS/ INCL SHRINKAGE, SWELLING & NECROSIS OF RENAL TUBULAR EPITHELIUM, ARTERIOLITIS, MILD HEPATITIS, MYOCARDITIS, CONGESTIVE ENCEPHALITIS & SOME ADRENAL HYPERTROPHY.
SUCROSE HAS SHOWN NO TOXICITY TO CORNEAS OF RABBITS WHEN APPLIED FOR 3 TO 7 HR IN NEUTRAL AQ SOLN...
...CANE SUGAR...OBSERVED TO CAUSE DIARRHEA, COLIC, INFLAMMATION OF KIDNEYS &...PETECHIAL HEMORRHAGES IN SPINAL DURA MATER OF HORSES.
For more Non-Human Toxicity Excerpts (Complete) data for SUCROSE (14 total), please visit the HSDB record page.
法规信息
FIFRA Requirements
Residues of sucrose are exempted from the requirement of a tolerance when used as a solid diluent, carrier or safener in accordance with good agricultural practices as inert (or occasionally active) ingredients in pesticide formulations applied to growing crops or to raw agricultural commodities after harvest.
Sucrose is exempted from the requirement of a tolerance when used as a solid diluent or carrier in accordance with good agricultural practice as inert (or occasionally active) ingredients in pesticide formulations applied to animals.
安全数据
- F
- 3
- wgk
- 2
- tsca
- TSCA listed
- 毒性
- LD50 orally in Rabbit: 29700 mg/kg
- RTECS号
- WN6500000
- 存储类别
- 11 - Combustible Solids
- 安全说明
- 24/25-37/39-26
- 海关编码
- 17019910
- 危险品标志
- Xi
- 危险类别码
- 36/37/38
- 毒害物质数据
- 57-50-1(Hazardous Substances Data)
- 职业暴露等级
- B
- 职业暴露限值
- TWA: 10 mg/m3 (total)
毒性防护
毒性GRAS(FDA,§184.1854,2000)。LD5029700mg/kg(大鼠,经口)。
化学与工业
药理信息
用途与制造
Uses
CIR ingredient: Sucrose
Obtained from cane sugar, sugar beet, and sorghum; Used as a sweetener; [ChemIDplus]
For Sucrose (USEPA/OPP Pesticide Code: 000023) there are 0 labels match. /SRP: Not registered for current use in the U.S., but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses./
FLAVOR BLENDER, ACCENTUATOR, MODIFIER & DISPERSING AGENT, SWEETENING, TEXTURE & BODYING AGENT FOR FOODS & BEVERAGES; RAW MATERIAL FOR NUMEROUS ORG CHEM & YEAST PRODN; LUBRICANT IN FOODS
Sweetener in foods and soft drinks, manufacture of syrups, source of invert sugar, confectionary, preserves and jams, demulcent, pharmaceutical products, caramel, chemical intermediate for detergents, emulsifying agents, and other sucrose derivatives.
Sweetening agent and food. Starting material in fermentative prodn of ethanol, butanol, glycerol, citric and levulinic acids. Used in pharmaceuticals as a flavor, as a preservative, as antioxidant (in form of invert sugar), as demulcent, as substitute for glycerol, as granulation agent and excipient for tablets, as coating for tablets. In plastics and cellulose industry, in rigid polyurethane foams, manuf of ink and of transparent soaps.
U.S. Exports
(1972) 7.06X10+8 G (CANE/BEET, RAW & REFINED)
(1975) 1.87X10+11 G
(1984) 2.79X10+10 g /Sugar cane, beet, crystalline structure or dry amorphous form, refined/
U.S. Imports
(1972) 4.77X10+12 G (CANE/BEET SUGAR & SYRUP)
(1975) 3.62X10+12 G
(1984) 3.28X10+12 g /Cane or beet sugars, syrups, molasses, NSPF (Raw Value)/
U.S. Production
2023: 250,000 - <550,000 lb
(1972) 5.01X10+13 G (CANE & BEET SUGAR)
(1975) 5.19X10+13 G (CANE AND BEET SUGAR)
Consumption Patterns
(DELIVERIES OF REFINED SUGAR): 35% WAS CONSUMED DIRECTLY FOR SWEETENING FOODS & BEVERAGES; THE REMAINING 65% WAS USED INDUSTRIALLY IN BEVERAGES (22%); IN BAKERY & CEREAL PRODUCTS (12%); IN CONFECTIONS (9%); IN CANNED, BOTTLED, & FROZEN FOODS (6%); IN ICE CREAM & DAIRY PRODUCTS (5%); IN MISC FOODS (5%); & IN NON-FOOD & UNSPECIFIED USES (6%) (1976)
Methods of Manufacturing
Obtained from sugar cane (Saccharum officinarum L, Gramineae) and sugar beet (Beta valgaris L, Chenopodiaceae). Sugar cane contains from 15-20% and sugar beet form 10-17% sucrose. Structure: Avery et al, J Chem Soc 1927, 2308; Beevers, Cochrane, Proc Roy Soc 190a, 257 (1947).
By crushing and extraction of sugarcane (Saccharum officinarum) with water or extraction of the sugar beet (Beta vulgaris) with water, evaporating, and purifying with lime, carbon, and various liquids. Also obtainable from sorghum by conventional methods.
Sucrose is extracted commercially from sugar maple
Formulations/Preparations
USEPA/OPP Pesticide Code 000023; Trade Names: None.
Grade: Reagent, USP, technical, refined.
Also sold as syrup .. liquid sugar
Use Classification
EPA Safer Chemical Functional Use Classes -> Processing Aids and Additives
Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern
Cosmetics -> Soothing; Humectant; Skin conditioning
General Manufacturing Information
Construction
.alpha.-D-Glucopyranoside, .beta.-D-fructofuranosyl: ACTIVE
CARBOHYDRATE (QV) PRODUCT OF PHOTOSYNTHESIS COMPRISED OF 1, 2, OR MORE SACCHAROSE GROUPS. ... SUGAR IS IMPORTANT SOURCE OF METABOLIC ENERGY IN FOODS, & ITS FORMATION IN PLANTS IS ESSENTIAL FACTOR IN LIFE PROCESS.
Sucrose is the most important industrial sugar
Sucrose was first synthesized enzymatically in the laboratory from potassium D-glucosyl-1-phosphate and D-fructose. The first chemical synthesis was accomplished by reaction of 3,4,6-tri-O-acetyl-1,2-anhydro-alpha-D-glucopyranose with 1,3,4,6-tetra-O-acetyl-D-fructofuranose
Traditionally, the standard /sweetening agent/ is sucrose, both in terms of quality of taste and taste profile
应用领域
简介蔗糖是一种双糖,由1个分子的葡萄糖和1个分子的果糖组成的。其原料主要是甘蔗(Saccharum spp.)和甜菜(Beta vulgaris),为无色结晶或白色结晶性的松散粉末,无臭,味甜。在水中极易溶解,在乙醇中微溶,无毒,可作为食品添加剂(甜味剂)。以蔗糖为主要成分的食糖根据纯度的由高到低又分为:冰糖、白砂糖、绵白糖和赤砂糖(也称红糖或黑糖),日常食用的白糖、红糖均是蔗糖。
用途营养性甜味剂;成型和组织结构剂。
用途蔗糖是最普通的食和糖,也用于制柠檬酸、焦糖、转化糖、透明肥皂等。蔗糖在高浓度时能抑制细菌生长,医药上可作防腐剂、抗氧剂的药片赋形剂等。1980年世界原糖产量为8710万t,其中蔗糖5200万t,甜菜糖3500万t。来自甘蔗和甜菜的蔗糖受自然条件的限制发展缓慢,世界缺糖情况较较严重。另外,各种特殊需要,促旱灾了新甜料的研究和发展,现在已经找出了许多天然甜料和合成甜料。试剂蔗糖用于1-萘酚的测定,也用于钙、镁分离及生物培养基的制备。
用途可广泛用于食品、化妆品、医药,同时也用于分析检测的标准品。
用途试剂蔗糖用于1-萘酚的测定,也用于钙、镁分离及生物培养基的制备。 细胞培养级用于蔗糖梯度纯化病毒和蛋白质。 植物细胞培养级用于植物细胞中的冷冻保护。 分子生物学级用于不连续蔗糖密度梯度的等密度离心法,如:从膜结合核糖体中分离mRNA。
用途多种物质保存液和辅助液
用途生物培养基。分离钙和镁。测定1-萘酚。络合滴定硼的掩蔽剂。有机微量分析测定碳、氢和氧的标准。
用途用作有机元素分析标准
制备方法
生产方法蔗糖大量来自甘蔗糖和甜菜,甘蔗含蔗糖约15-20%,甜菜含10-17%。其他各种果实、种子、叶、花、根中也有不同的含量。将甘蔗榨出法液或将甜菜切片用水提出糖汁,用石灰澄清法或兼用亚硫酸饱充法,除去糖汁中的杂质,过滤后将滤液真空蒸浓,再结晶分离而得粗糖,再经脱色、重结晶而得精糖。
生产方法由甘蔗或甜菜经压榨或渗滤后澄清、蒸发、结晶而得。
上下游产品信息
下游产品
试剂价格
- A15583 · 2500g
- 蔗糖Sucrose — 845元
- S3598 · 100mg
- 蔗糖Sucrose — 811.42元
相关反应
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