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乙二胺二盐酸盐
盐酸乙二胺 · 二盐酸乙二胺 · 盐酸二氨基乙烷 · 乙二胺二盐酸盐 · 乙撑二胺二盐酸盐 · 盐酸乙二胺标准品 · 盐酸乙二胺对照品 · 1,2-乙二胺二盐酸盐
标识与物理属性
| CAS No. | 333-18-6 |
|---|---|
| 分子式 | C2H10Cl2N2 |
| 平均分子量 | 133.02 g/mol |
| 单同位素质量 | 132.0221037 g/mol |
| SMILES | Cl.Cl.NCCN |
| InChIKey | OHHBFEVZJLBKEH-UHFFFAOYSA-N |
| PubChem CID | 9521 |
| ChEBI | CHEBI:53626 |
| EC No. | 206-369-6 |
| DTXSID | DTXSID5043920 |
| 中文名 | 乙二胺二盐酸盐 |
化学与物理性质
| 极性表面积 | 52 |
|---|---|
| 氢键供体 | 4 |
| 氢键受体 | 2 |
| 可旋转键 | 1 |
| 重原子 | 6 |
| 形式电荷 | 0 |
| 复杂度 | 6 |
| Physical Description | White crystalline solidHygroscopic[Sigma-Aldrich MSDS] |
| 熔点 | >300 °C(lit.) |
| 堆积密度 | 650kg/m3 |
| 密度 | 1.46 g/cm3 |
| 储存条件 | Store below +30°C. |
| 溶解性 | water: soluble100mg/mL, clear, colorless to very faintly yellow300 g/L (20 ºC) |
| 形态 | Crystalline Powder |
| 颜色 | White to off-white |
| pH | 5 (100g/l, H2O, 20℃) |
| 敏感性 | Hygroscopic |
| BRN | 3665235 |
| 稳定性 | Stable. Incompatible with strong oxidizing agents. |
| InChI | InChI=1S/C2H8N2.2ClH/c3-1-2-4/h1-4H22*1H |
| InChIKey | OHHBFEVZJLBKEH-UHFFFAOYSA-N |
| SMILES | C(N)CN.Cl.Cl |
| CAS 数据库 | 333-18-6(CAS DataBase Reference) |
| EPA化学物质信息 | Ethylenediamine dihydrochloride (333-18-6) |
化学性质
乙二胺二盐酸盐的化学本质是乙二胺，该物质在进行化学转化反应之前一般需要用中强碱进行酸碱中和反应以释放出相应的乙二胺，进而参与后续的化学转化反应。该物质在水中的溶液呈中性，但是它在醇类有机溶剂中的溶解性较差。
安全与法规
| GHS 分类 | DangerH302 (94.4%): Harmful if swallowed [Warning Acute toxicity, oral]H315 (93%): Causes skin irritation [Warning Skin corrosion/irritation]H317 (93%): May cause an allergic skin reaction [Warning Sensitization, Skin]H319 (93%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]H334 (88.7%): May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory]H335 (88.7%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposureRespiratory tract irritation]P233, P260, P261, P264, P264+P265, P270, P271, P272, P280, P284, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P333+P317, P337+P317, P342+P316, P362+P364, P403, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 71 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. |
|---|---|
| 法规信息 | Chemical: 1,2-Ethanediamine, dihydrochlorideEthylenediammonium dichloride: Does not have an individual approval but may be used under an appropriate group standard |
| 危害概述 | Causes allergic dermatitis in 48-hr constant dermal studies of humans[RTECS] A skin and strong eye irritantMay cause skin and respiratory sensitizationHarmful by ingestionReproductive and developmental toxicity observed in experimental animals[Sigma-Aldrich MSDS] See Ethylenediamine. |
| Hazard Classes and Categories | Acute Tox. 4 (94.4%)Skin Irrit. 2 (93%)Skin Sens. 1 (93%)Eye Irrit. 2A (93%)Resp. Sens. 1 (88.7%)STOT SE 3 (88.7%) |
| Protective Action Criteria (PAC) | 2.7 [mg/m3]29 [mg/m3]180 [mg/m3] |
| 不良影响 | Skin Sensitizer - An agent that can induce an allergic reaction in the skin.Asthma - Reversible bronchoconstriction (narrowing of bronchioles) initiated by the inhalation of irritating or allergenic agents. |
| 水危害等级（WGK） | 2 |
| TSCA 清单状态 | TSCA listed |
| 毒性 | LD50 orally in Rabbit: 3250 mg/kg LD50 dermal Rabbit > 2000 mg/kg |
| RTECS 号 | KV3850000 |
| 储存类别 | 11 - Combustible Solids |
| 安全说明（S） | 22-26-36/37-45 |
| 海关编码 | 29212100 |
| 危险品标志 | Xn |
| 危险类别 | Acute Tox. 4 OralEye Irrit. 2Resp. Sens. 1Skin Irrit. 2Skin Sens. 1STOT SE 3 |
| 危险类别码（R） | 22-36/37/38-42/43 |
用途与应用
简介
乙二胺二盐酸盐是一种有机中间体，有文献报道其可用于制备涉及除草活性的吡啶基-/嘧啶基-吡嗪衍生物以及琥珀酸脱氢酶抑制剂类杀菌剂。
应用
乙二胺二盐酸盐在生物化学领域中广泛用作基础试剂，其溶解性和稳定性使其成为常用的实验试剂。其在农业和医药领域中具有一定的应用，它可用于吡嗪类杀菌剂的制备。在染料化学合成领域，该物质也具有一定的应用，它可用作为催化剂、还原剂或反应中间体参与染料分子的合成反应。
用途
乙二胺二盐酸盐可用作分析试剂和固化剂，也用于染料合成。