DL-苯丙氨酸

Dl-Phenylalanine

HCID 994CAS 150-30-1
子结构检索查找相似结构

基本信息

标准SMILES
NC(Cc1ccccc1)C(=O)O
InChIKey
COLNVLDHVKWLRT-UHFFFAOYSA-N
分子式
C9H11NO2
平均分子量
165.19 g/mol
单同位素质量
165.07897859

概述

Phenylalanine is an aromatic amino acid that is alanine in which one of the methyl hydrogens is substituted by a phenyl group. It has a role as a Daphnia magna metabolite. It is an alpha-amino acid and an aromatic amino acid. It contains a benzyl group. It is a conjugate base of a phenylalaninium. It is a conjugate acid of a phenylalaninate.

名称与标识

首选名称
Dl-Phenylalanine
IUPAC
2-amino-3-phenylpropanoic acid
中文名
DL-苯丙氨酸
英文名
DL-Phenylalanine
分子式
C9H11NO2
分子量
165.19

名称与别名

DL-PHENYLALANINE150-30-1DL-3-PhenylalaninePhenylalanine DL-formPhenylalanine, dl-DL-2-Amino-3-phenylpropanoic acidFEMA No. 3726NSC 9959DTXSID9023463d,l-phenylalanineEINECS 205-756-7CCRIS 8601
展开更多名称
DL-苯丙苯胺基丙酸DL-苯丙氨酸DL-苯并氨酸DL-笨丙氨酸DL-苯基并氨酸DL-苯胺基丙酸DL-N-苯丙氨酸DL-Α-苯丙酸氨DL-苯丙氨酸 标准品3-AMINO-3-PHENYLPROPANOIC ACIDH-DL-PHE-OHDL-PHENYALANINE3 AMINO-PHENYLPROPIONIC ACIDD,L-PHEDLPA 375FEMA 3726DL-Phenylalani
AI3-18436PHENYLALANINE DL8P946UF12SNSC-9959DL-PHENYLALANINE [FCC]DTXCID103463DL-PHENYLALANINE [FHFI]DL-PHENYLALANINE [WHO-DD]

数据库标识

CAS
150-30-1、30394-07-1、63-91-2、673-06-3
PubChem CID
994
DTXSID
DTXSID9023463
ChEMBL
CHEMBL25080
ChEBI
CHEBI:28044
UNII
8P946UF12S
EC Number
205-756-7
Nikkaji
J1.258K

性质

结构计算性质

XLogP
-1.5
极性表面积
63.3 Ų
氢键供体
2
氢键受体
3
可旋转键
3
重原子
12

实验与物化性质

Chemical ClassesBiological Agents -> Amino Acids and Derivatives
DrugsPharmaceuticals
Food AdditivesFLAVOR ENHANCER, FLAVORING AGENT OR ADJUVANT -> FDA Substance added to food
Flavoring AgentsEU Flavoring substances
Solubility · 2 条

Soluble in water and dilute mineral acid and alkali hydroxide solutions

Slightly soluble (in ethanol)

Vapor Pressure0.00000005 [mmHg]

物理化学性质

熔点
266 · 266-267 °C (dec.) (lit.)
沸点
293.03 °C · 293.03°C (rough estimate)
密度
1.1603 · 1.1603 (rough estimate)
折射率
1.52 · 1.5200 (estimate)
FEMA
3726 · 3726 | D,L-PHENYLALANINE
储存条件
Store at RT.

化学性质

白色小片状结晶或结晶性粉末。无臭。无旋光性。溶于水、稀无机酸和碱性氢氧化物溶液，极难溶于乙醇。具有与L-苯丙氨酸相同的生理效能。

安全与法规

GHS分类

GHS Classification · 3 条

This chemical does not meet GHS hazard criteria for 99.1% (112 of 113) of all reports.

Not Classified

Aggregated GHS information provided per 113 reports by companies from 2 notifications to the ECHA C&L Inventory.

危害信息

Regulatory Information · 3 条

Chemical: DL-Phenylalanine

Commission Regulation (EC) No 1565/2000 (Repealed by Com. Implementing Reg. (EU) No 872/2012)

Phenylalanine: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - DL-Phenylalanine: Human health tier I assessment
Hazards SummarySafe when used as a flavoring agent in food; [EFSA] Not considered hazardous by GHS classification; [Sigma-Aldrich MSDS] See Phenylalanine.
Hazard Classes and CategoriesNot Classified

安全数据

wgk
3
tsca
TSCA listed
hazard_note
Irritant
存储类别
11 - Combustible Solids
安全说明
37/39-24/25-45-36/37/39-27-26
海关编码
29224995

毒性防护

毒性LD505452mg/kg(大鼠，腹腔注射)。

化学与工业

用途与制造

UsesUsed as a component of aspartame and as a nutrient; [Merck Index] Used as a flavoring agent; [FDA]
Use Classification · 2 条

Flavoring Agents -> JECFA Flavorings Index

Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes

General Manufacturing InformationPhenylalanine: ACTIVE
应用领域 · 4 条

用途用作营养增补剂、食品添加剂

用途营养增补剂、饮料添加剂。可作为医药原料，拆分可作为氨基酸及甜味素中间体。

用途DL-苯丙氨酸是人体必需氨基酸之一，用作营养增补剂

用途用作营养增补剂、食品添加剂

制备方法

生产方法由乙酰L-苯丙氨酸在碱性条件下消旋，再用盐酸水解以除去乙酰基后中和、精制而成。

上下游产品信息

试剂价格

HY-B1732R · 25 mg
DL-苯丙氨酸DL-3-Phenylalanine (Standard) — 260元
HY-B1732R · 50 mg
DL-苯丙氨酸DL-3-Phenylalanine (Standard) — 400元

供应商50 家

国药集团化学试剂有限公司86-21-63210123 · [email protected]
北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
上海如吉生物科技发展有限公司+86-21-65211385-8001 36031160 · [email protected]

相关反应

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