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1,5-二甲基-1H-吡唑-3-甲醇 → 8-(3,5-Bis-trifluoromethyl-benzoyl)-1-(2-chloro-phenyl)-3-(1,5-dimethyl-1H-pyrazol-3-ylmethyl)-1,3,8-triaza-spiro[4.5]decane-2,4-dione
参与物
| 角色 | 名称 | HCID | 投料 |
|---|---|---|---|
| 反应物 | 1,5-二甲基-1H-吡唑-3-甲醇 | HCID 2776366 | — |
| 反应物 | 8-(3,5-Bis-trifluoromethyl-benzoyl)-1-(2-chloro-phenyl)-1,3,8-triaza-spiro[4.5]decane-2,4-dione | HCID 18401685 | — |
| 产物 | 8-(3,5-Bis-trifluoromethyl-benzoyl)-1-(2-chloro-phenyl)-3-(1,5-dimethyl-1H-pyrazol-3-ylmethyl)-1,3,8-triaza-spiro[4.5]decane-2,4-dione | HCID 18401676 | — |
反应步骤
The title compound, MS: m/e=627.1 (M+), was prepared in accordance with the general method of example 121 from 8-(3,5-bis-trifluoromethyl-benzoyl)-1-(2-chloro-phenyl)-1,3,8-triaza-spiro[4.5]decane-2,4-dione and 1,5 -dimethylpyrazole-3-methanol.
来源与证据
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 专利号 | US06482829B2 |
| 来源数据集 | uspto-grants-2002_11 |
| ORD ID | ord-b82c1acfa0b2455b90a2669f3bf03dc0 |
| 来源说明 | uspto-grants-2002_11 |