氢氧化锂 → HCID 23713290，化合物

HRID 1074219

反应方程式

HRID 1074219 反应方程式
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([S:8]([OH:11])(=[O:10])=[O:9])[N:3]=1.[OH-].[Li+:13]>O>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([S:8]([O-:11])(=[O:10])=[O:9])[N:3]=1.[Li+:13]

参与物

4

反应物 2

HCID 3939氢氧化锂HCID 27628906-氯吡啶-2-磺酰酸

产物 1

HCID 23713290HCID 23713290，化合物收率 89.5%

试剂、催化剂与溶剂 1

HCID 962聚[6-[4-(4-氰基苯基)苯氧基]己基甲基丙烯酸酯]溶剂

实验过程

Into a 200 ml egg-plant type flask, 785.2 mg (4.06 mmol) of 2-chloropyridine-6-sulfonic acid was charged, then dissolved with an addition of 2 ml of water and neutralized with an aqueous lithium hydroxide solution. The solvent was distilled off under reduced pressure, and after an addition of 100 ml of 2-propanol, the mixture was heated. Insoluble matters were removed by filtration, and the solvent was distilled under reduced pressure to obtain 725 mg (89.5%) of lithium 2-chloropyridine-6-sulfonate as crystalline solid. Purification was conducted by recrystallization from 2-propanol.

后处理

  1. distillationThe solvent was distilled off under reduced pressure
  2. additionafter an addition of 100 ml of 2-propanol
  3. temperaturethe mixture was heated
  4. customInsoluble matters were removed by filtration
  5. distillationthe solvent was distilled under reduced pressure

来源与证据

ORD记录
ord-2e42b5f8e4c34f58b2ae45ad47584d6d
来源数据集
uspto-grants-1990_11
专利号
US04973697

关联笔记

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