氟化钠 → 2,2,3,3-tetrafluoro-3-(1,1,2,2,3,3,3-heptafluoropropoxy)propanoyl Fluoride

HRID 1356601

反应方程式

HRID 1356601 反应方程式
[C:1]([C:5]([C:8]([O:11][C:12]([C:15]([C:18]([O:21]C(C(OC(C(C(F)(F)F)(F)F)(F)F)(C(F)(F)F)F)=O)(F)[F:19])([F:17])[F:16])([F:14])[F:13])([F:10])[F:9])([F:7])[F:6])([F:4])([F:3])[F:2].[F-].[Na+]>>[C:1]([C:5]([C:8]([O:11][C:12]([C:15]([C:18]([F:19])=[O:21])([F:17])[F:16])([F:14])[F:13])([F:10])[F:9])([F:7])[F:6])([F:4])([F:3])[F:2]

参与物

3

反应物 2

HCID 5235氟化钠HCID 131723953CF3CF2CF2Ocf2CF2CF2ococf(CF3)ocf2CF2CF3

产物 1

HCID 117390512,2,3,3-tetrafluoro-3-(1,1,2,2,3,3,3-heptafluoropropoxy)propanoyl Fluoride收率 57%

反应条件

温度
120 °C

实验过程

CF3CF2CF2OCF2CF2CF2OCOCF(CF3)OCF2CF2CF3 (0.8 g) obtained in Example 42 was charged into a flask together with a NaF powder (0.01 g) and heated at 120° C. for 10 hours in an oil bath with vigorous stirring. At an upper portion of the flask, a reflux condenser adjusted to a temperature of 20° C. was installed. After cooling, a liquid sample (0.7 g) was recovered. By GC-MS, it was confirmed that CF3CF(OCF2CF2CF3)COF and the above-identified compound were the main products. The yield was 57.0%.

后处理

  1. customadjusted to a temperature of 20° C.
  2. temperatureAfter cooling
  3. customa liquid sample (0.7 g) was recovered

来源与证据

ORD记录
ord-232f16a39a08459883db72c3e3f7be86
来源数据集
uspto-grants-2003_07
专利号
US06586626B2

关联笔记

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