三苯基膦 → (3,5-二甲氧基苄基)三苯基溴化鏻

HRID 1389187

反应方程式

HRID 1389187 反应方程式
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:8]=[C:9]([O:11][CH3:12])[CH:10]=1)[CH2:6][Br:7].[C:13]1([P:19]([C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)[C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>C(#N)C>[Br-:7].[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:8]=[C:9]([O:11][CH3:12])[CH:10]=1)[CH2:6][P+:19]([C:20]1[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=1)([C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1)[C:13]1[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=1

参与物

4

反应物 2

HCID 11776三苯基膦HCID 12744903,5-二甲氧基溴苄

产物 1

HCID 10962038(3,5-二甲氧基苄基)三苯基溴化鏻

试剂、催化剂与溶剂 1

HCID 6342乙腈溶剂

实验过程

The 3,5-dimethoxybenzyl triphenylphosphonium bromide is prepared by refluxing a mixture of 3,5-dimethoxybenzyl bromide (12 g.) and triphenylphosphine (14.2 g.) in acetonitrile (200 ml.) for one hour. The reaction mixture is then cooled and the crystalline product recovered by filtration, washed with ether and dried (20 g.); m.p. 269°-270° C.

后处理

  1. temperatureby refluxing
  2. temperatureThe reaction mixture is then cooled
  3. filtrationthe crystalline product recovered by filtration
  4. washwashed with ether
  5. customdried (20 g.)

来源与证据

ORD记录
ord-38dd8724eeed44b5b7e0b0172da1adff
来源数据集
uspto-grants-1981_01
专利号
US04243674

关联笔记

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