2-甲氨基苯并噻唑 → 3-甲基-2-亚氨基苯并噻唑

HRID 1414107

反应方程式

HRID 1414107 反应方程式
COC1C=CC(NC(N)=S)=CC=1.C1(NC(NC)=S)C=CC=CC=1.[C:24]1([N:30]([CH3:34])[C:31]([NH2:33])=[S:32])[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1.CNC1SC2C=CC=CC=2N=1>>[CH3:34][N:30]1[C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][C:25]=2[S:32][C:31]1=[NH:33]

参与物

5

反应物 4

HCID 281602-甲氨基苯并噻唑HCID 667549对甲氧基苯基硫脲HCID 6982941-甲基-3-苯基硫脲HCID 723631N-甲基-N-苯基硫脲

产物 1

HCID 846423-甲基-2-亚氨基苯并噻唑

实验过程

When using, instead of 4-methoxyphenyl-thiourea of Examples 89 and 90, equivalent amounts of N-phenyl-N'-methyl-thiourea or N-phenyl-N-methyl-thiourea, the other conditions remaining the same, 2-methylamino-benzthiazole (m.p. 137° C.) or 3-methyl-2-imino-benzthiazoline (m.p. 122°) is obtained in an equally good yield and in a high purity.

来源与证据

ORD记录
ord-d2fea834efa7435185c3ef5a025ed5be
来源数据集
uspto-grants-1981_02
专利号
US04252963

关联笔记

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